Crystal structure of the N-terminal domain of the human mitochondrial calcium uniporter

Summary for 4XTB

DescriptorCalcium uniporter protein, mitochondrial, TETRAETHYLENE GLYCOL (3 entities in total)
Functional Keywordscalcium channel, membrane protein, mitochondria, transport protein
Biological sourceHomo sapiens (Human)
Cellular locationMitochondrion inner membrane ; Multi-pass membrane protein  Q8NE86
Total number of polymer chains1
Total molecular weight14279.37
Primary citation
Lee, Y.,Min, C.K.,Kim, T.G.,Song, H.K.,Lim, Y.,Kim, D.,Shin, K.,Kang, M.,Kang, J.Y.,Youn, H.S.,Lee, J.G.,An, J.Y.,Park, K.R.,Lim, J.J.,Kim, J.H.,Kim, J.H.,Park, Z.Y.,Kim, Y.S.,Wang, J.,Kim, D.H.,Eom, S.H.
Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter.
Embo Rep., 16:1318-1333, 2015
PubMed: 26341627 (PDB entries with the same primary citation)
DOI: 10.15252/embr.201540436
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.175400 11.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21