6QBY
| Crystal structure of VASH 2 in complex with SVBP | Descriptor: | Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2 | Authors: | Choi, S.R, Olieric, V, Steinmetz, M.O, Olieric, N. | Deposit date: | 2018-12-24 | Release date: | 2019-04-24 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex. Nat.Struct.Mol.Biol., 26, 2019
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7ZCW
| Cryo-EM structure of GMPCPP-microtubules in complex with VASH2-SVBP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Choi, S.R, Blum, T, Steinmetz, M.O. | Deposit date: | 2022-03-29 | Release date: | 2022-12-14 | Last modified: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | VASH1-SVBP and VASH2-SVBP generate different detyrosination profiles on microtubules. J.Cell Biol., 222, 2023
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7CJ2
| Crystal structure of the Fab antibody complexed with human YKL-40 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase 3-like 1 (Cartilage glycoprotein-39), isoform CRA_a, ... | Authors: | Choi, S, Na, J.H, Lee, S.J, Woo, J.R, Kim, D.Y, Hong, J.T, Lee, W.K. | Deposit date: | 2020-07-09 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the Fab antibody complexed with human YKL-40 To Be Published
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5HTO
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5HS4
| Plasmdoium Vivax Lactate dehydrogenase | Descriptor: | L-lactate dehydrogenase | Authors: | Choi, S.J, Ban, C. | Deposit date: | 2016-01-25 | Release date: | 2016-10-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.339 Å) | Cite: | Crystal structure of a DNA aptamer bound to PvLDH elucidates novel single-stranded DNA structural elements for folding and recognition Sci Rep, 6, 2016
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5HRU
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7E42
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3GOP
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3W5K
| Crystal structure of Snail1 and importin beta complex | Descriptor: | Importin subunit beta-1, ZINC ION, Zinc finger protein SNAI1 | Authors: | Choi, S, Yamashita, E, Yasuhara, N, Song, J, Son, S.Y, Won, Y.H, Shin, Y.S, Sekimoto, T, Park, I.Y, Yoneda, Y, Lee, S.J. | Deposit date: | 2013-01-30 | Release date: | 2014-03-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin beta. Acta Crystallogr.,Sect.D, 70, 2014
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8HNJ
| Domain-stabilized glutamine-binding protein | Descriptor: | GLUTAMINE, Glutamine ABC transporter, periplasmic glutamine-binding protein GlnH | Authors: | Choi, S.H, Park, J.H, Seo, M.H, Park, K.W, Lee, W.K. | Deposit date: | 2022-12-08 | Release date: | 2023-07-19 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Domain-wise dissection of thermal stability enhancement in multidomain proteins. Int.J.Biol.Macromol., 237, 2023
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2A4V
| Crystal Structure of a truncated mutant of yeast nuclear thiol peroxidase | Descriptor: | Peroxiredoxin DOT5 | Authors: | Choi, J, Choi, S, Chon, J.-K, Choi, J, Cha, M.-K, Kim, I.-H, Shin, W. | Deposit date: | 2005-06-29 | Release date: | 2006-03-14 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the C107S/C112S mutant of yeast nuclear 2-Cys peroxiredoxin Proteins, 61, 2005
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8K7C
| Outward-facing structure of human ABCB6 W546A mutant (ADP/VO4-bound) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family B member 6, MAGNESIUM ION, ... | Authors: | Jin, M.S, Lee, S.S, Park, J.G, Jang, E, Choi, S.H, Kim, S, Kim, J.W. | Deposit date: | 2023-07-26 | Release date: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state. Commun Biol, 6, 2023
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8K7B
| post-occluded structure of human ABCB6 W546A mutant (ADP/VO4-bound) | Descriptor: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ADP ORTHOVANADATE, ATP-binding cassette sub-family B member 6, ... | Authors: | Jin, M.S, Lee, S.S, Park, J.G, Jang, E, Choi, S.H, Kim, S, Kim, J.W. | Deposit date: | 2023-07-26 | Release date: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state. Commun Biol, 6, 2023
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8CU6
| Crystal structure of A2AAR-StaR2-S277-bRIL in complex with a novel A2a antagonist, LJ-4517 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R,3R,4R)-2-[(8P)-6-amino-2-(hex-1-yn-1-yl)-8-(thiophen-2-yl)-9H-purin-9-yl]oxolane-3,4-diol, Adenosine receptor A2a,Soluble cytochrome b562, ... | Authors: | Shiriaeva, A, Park, D.-J, Kim, G, Lee, Y, Hou, X, Jarhad, D.B, Kim, G, Yu, J, Hyun, Y.E, Kim, W, Gao, Z.-G, Jacobson, K.A, Han, G.W, Stevens, R.C, Jeong, L.S, Choi, S, Cherezov, V. | Deposit date: | 2022-05-16 | Release date: | 2022-08-31 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A 2A Adenosine Receptor. J.Med.Chem., 65, 2022
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8CU7
| Crystal structure of A2AAR-StaR2-bRIL in complex with a novel A2a antagonist, LJ-4517 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R,3R,4R)-2-[(8P)-6-amino-2-(hex-1-yn-1-yl)-8-(thiophen-2-yl)-9H-purin-9-yl]oxolane-3,4-diol, Adenosine receptor A2a,Soluble cytochrome b562, ... | Authors: | Shiriaeva, A, Park, D.-J, Kim, G, Lee, Y, Hou, X, Jarhad, D.B, Kim, G, Yu, J, Hyun, Y.E, Kim, W, Gao, Z.-G, Jacobson, K.A, Han, G.W, Stevens, R.C, Jeong, L.S, Choi, S, Cherezov, V. | Deposit date: | 2022-05-16 | Release date: | 2022-08-31 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A 2A Adenosine Receptor. J.Med.Chem., 65, 2022
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1QXH
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8GSI
| Structure of the cobolimab Fab | Descriptor: | heavy chain, light chain, nanobody | Authors: | Heo, Y.S, Choi, S.B. | Deposit date: | 2022-09-06 | Release date: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Crystal structure of the Fab fragment of cobolimab, an investigational antibody targeting Tim-3 for immune-oncology. To Be Published
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8HEJ
| Crystal structure of Transthyretin in complex with a covalent inhibitor trans-styrylpyrazole | Descriptor: | 2,4,6-trifluorobenzaldehyde, 2,6-dibromo-4-[(E)-2-(3,5-dimethyl-1H-pyrazol-4-yl)ethenyl]phenol, Transthyretin | Authors: | Kim, H, Choi, S, Lee, C. | Deposit date: | 2022-11-08 | Release date: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Crystal structure of Transthyretin in complex with a covalent inhibitor trans-styrylpyrazole To Be Published
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7VFI
| Cryo-EM structure of the mouse TAPL (9mer-peptide bound) | Descriptor: | ABC-type oligopeptide transporter ABCB9, ARG-ARG-TYR-GLN-LYS-SER-THR-GLU-LEU, CHOLESTEROL HEMISUCCINATE | Authors: | Park, J.G, Kim, S, Jang, E, Choi, S.H, Han, H, Kim, J.W, Ju, S, Min, D.S, Jin, M.S. | Deposit date: | 2021-09-13 | Release date: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (3.98 Å) | Cite: | The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase. Nat Commun, 13, 2022
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4ZJ2
| Crystal Structure of p-acrylamido-phenylalanine modified TEM1 beta-lactamase from Escherichia coli :E166N mutant | Descriptor: | Beta-lactamase TEM | Authors: | Xiao, H, Nasertorabi, F, Choi, S, Han, G.W, Reed, S.A, Stevens, C.S, Schultz, P.G. | Deposit date: | 2015-04-28 | Release date: | 2015-05-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Exploring the potential impact of an expanded genetic code on protein function. Proc.Natl.Acad.Sci.USA, 112, 2015
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4ZJ1
| Crystal Structure of p-acrylamido-phenylalanine modified TEM1 beta-lactamase from Escherichia coli : V216AcrF mutant | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-lactamase TEM, DI(HYDROXYETHYL)ETHER, ... | Authors: | Xiao, H, Nasertorabi, F, Choi, S, Han, G.W, Reed, S.A, Stevens, R.C, Schultz, P.G. | Deposit date: | 2015-04-28 | Release date: | 2015-05-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Exploring the potential impact of an expanded genetic code on protein function. Proc.Natl.Acad.Sci.USA, 112, 2015
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4ZJ3
| Crystal structure of cephalexin bound acyl-enzyme intermediate of Val216AcrF mutant TEM1 beta-lactamase from Escherichia coli: E166N and V216AcrF mutant. | Descriptor: | Beta-lactamase TEM | Authors: | Xiao, H, Nasertorabi, F, Choi, S, Han, G.W, Reed, S.A, Stevens, R.C, Schultz, P.G. | Deposit date: | 2015-04-29 | Release date: | 2015-05-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Exploring the potential impact of an expanded genetic code on protein function. Proc.Natl.Acad.Sci.USA, 112, 2015
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4Y1H
| Crystal structure of K33 linked tri-Ubiquitin | Descriptor: | 1,2-ETHANEDIOL, Ubiquitin-40S ribosomal protein S27a | Authors: | Kristariyanto, Y.A, Abdul Rehman, S.A, Choi, S.Y, Ritorto, S, Campbell, D.G, Morrice, N.A, Toth, R, Kulathu, Y. | Deposit date: | 2015-02-07 | Release date: | 2015-03-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations. Biochem.J., 467, 2015
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4XYZ
| Crystal structure of K33 linked di-Ubiquitin | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, IODIDE ION, ... | Authors: | Kristariyanto, Y.A, Abdul Rehman, S.A, Choi, S.Y, Ritorto, S, Campbell, D.G, Morrice, N.A, Toth, R, Kulathu, Y. | Deposit date: | 2015-02-03 | Release date: | 2015-03-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations. Biochem.J., 467, 2015
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7V5C
| Cryo-EM structure of the mouse ABCB9 (ADP.BeF3-bound) | Descriptor: | ABC-type oligopeptide transporter ABCB9, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Park, J.G, Kim, S, Jang, E, Choi, S.H, Han, H, Kim, J.W, Ju, S, Min, D.S, Jin, M.S. | Deposit date: | 2021-08-17 | Release date: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase. Nat Commun, 13, 2022
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