8GSI

Structure of the cobolimab Fab

Summary for 8GSI

• Entry DOI: 10.2210/pdb8gsi/pdb
• Descriptor: light chain, heavy chain, nanobody, ... (4 entities in total)
• Functional Keywords: cobolimab, tim-3. immume checkpoint, cancer immunotherapy, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 61662.33

Authors

Heo, Y.S.,Choi, S.B. (deposition date: 2022-09-06, release date: 2023-09-06)

• Primary citation: Heo, Y.S.,Choi, S.B.; Crystal structure of the Fab fragment of cobolimab, an investigational antibody targeting Tim-3 for immune-oncology.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.02 Å)