7VFI

Cryo-EM structure of the mouse TAPL (9mer-peptide bound)

Summary for 7VFI

• Entry DOI: 10.2210/pdb7vfi/pdb
• EMDB information: 31955
• Descriptor: ABC-type oligopeptide transporter ABCB9, ARG-ARG-TYR-GLN-LYS-SER-THR-GLU-LEU, CHOLESTEROL HEMISUCCINATE (3 entities in total)
• Functional Keywords: tapl, peptide transporter, lipid floppase, membrane protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 3
• Total formula weight: 170737.13

Authors

Park, J.G.,Kim, S.,Jang, E.,Choi, S.H.,Han, H.,Kim, J.W.,Ju, S.,Min, D.S.,Jin, M.S. (deposition date: 2021-09-13, release date: 2022-10-19)

• Primary citation: Park, J.G.,Kim, S.,Jang, E.,Choi, S.H.,Han, H.,Ju, S.,Kim, J.W.,Min, D.S.,Jin, M.S.; The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase.; Nat Commun, 13:5851-5851, 2022; PubMed: 36195619; DOI: 10.1038/s41467-022-33593-2

Experimental method

ELECTRON MICROSCOPY (3.98 Å)