8K7C

Outward-facing structure of human ABCB6 W546A mutant (ADP/VO4-bound)

Summary for 8K7C

• Entry DOI: 10.2210/pdb8k7c/pdb
• Related: 7DNY 7DNZ
• EMDB information: 36938
• Descriptor: ATP-binding cassette sub-family B member 6, ADENOSINE-5'-DIPHOSPHATE, VANADATE ION, ... (4 entities in total)
• Functional Keywords: atp-binding cassette transporter, mitochondrial transporter, outward-facing state, adp/vo4-bound, abcb6, membrane protein, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 132872.48

Authors

Jin, M.S.,Lee, S.S.,Park, J.G.,Jang, E.,Choi, S.H.,Kim, S.,Kim, J.W. (deposition date: 2023-07-26, release date: 2023-10-04)

• Primary citation: Lee, S.S.,Park, J.G.,Jang, E.,Choi, S.H.,Kim, S.,Kim, J.W.,Jin, M.S.; W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state.; Commun Biol, 6:960-960, 2023; PubMed: 37735522; DOI: 10.1038/s42003-023-05339-3

Experimental method

ELECTRON MICROSCOPY (3.9 Å)