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8K7C

Outward-facing structure of human ABCB6 W546A mutant (ADP/VO4-bound)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
ATP-binding cassette sub-family B member 6polymer58765869.82UniProt (Q9NP58)
Pfam (PF00664)
Pfam (PF00005)
Homo sapiens (human)ABC-type heme transporter ABCB6,Mitochondrial ABC transporter 3,Mt-ABC transporter 3,P-glycoprotein-related protein,Ubiquitously-expressed mammalian ABC half transporter
2C, F
(A, B)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
3D, G
(A, B)
VANADATE IONnon-polymer114.92Chemie (VO4)
4E, H
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
Sequence modifications
A, B: 240 - 826 (UniProt: Q9NP58)
PDBExternal DatabaseDetails
Ala 546Trp 546engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight131739.6
Non-Polymers*Number of molecules6
Total formula weight1132.9
All*Total formula weight132872.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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