8K7B
post-occluded structure of human ABCB6 W546A mutant (ADP/VO4-bound)
Summary for 8K7B
Entry DOI | 10.2210/pdb8k7b/pdb |
Related | 7DNY 7DNZ |
EMDB information | 36937 |
Descriptor | ATP-binding cassette sub-family B member 6, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ADP ORTHOVANADATE, ... (4 entities in total) |
Functional Keywords | atp-binding cassette transporter mitochondrial transporter, post-occluded, adp/vo4-bound, abcb6, membrane protein, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 135005.26 |
Authors | Jin, M.S.,Lee, S.S.,Park, J.G.,Jang, E.,Choi, S.H.,Kim, S.,Kim, J.W. (deposition date: 2023-07-26, release date: 2023-10-04) |
Primary citation | Lee, S.S.,Park, J.G.,Jang, E.,Choi, S.H.,Kim, S.,Kim, J.W.,Jin, M.S. W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state. Commun Biol, 6:960-960, 2023 Cited by PubMed: 37735522DOI: 10.1038/s42003-023-05339-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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