8K7B

post-occluded structure of human ABCB6 W546A mutant (ADP/VO4-bound)

Summary for 8K7B

Entry DOI	10.2210/pdb8k7b/pdb
Related	7DNY 7DNZ
EMDB information	36937
Descriptor	ATP-binding cassette sub-family B member 6, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ADP ORTHOVANADATE, ... (4 entities in total)
Functional Keywords	atp-binding cassette transporter mitochondrial transporter, post-occluded, adp/vo4-bound, abcb6, membrane protein, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	135005.26
Authors	Jin, M.S.,Lee, S.S.,Park, J.G.,Jang, E.,Choi, S.H.,Kim, S.,Kim, J.W. (deposition date: 2023-07-26, release date: 2023-10-04)
Primary citation	Lee, S.S.,Park, J.G.,Jang, E.,Choi, S.H.,Kim, S.,Kim, J.W.,Jin, M.S. W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state. Commun Biol, 6:960-960, 2023 Cited by PubMed: 37735522 DOI: 10.1038/s42003-023-05339-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation