8K7B
post-occluded structure of human ABCB6 W546A mutant (ADP/VO4-bound)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ATP-binding cassette sub-family B member 6 | polymer | 590 | 66214.2 | 2 | UniProt (Q9NP58) Pfam (PF00664) Pfam (PF00005) | Homo sapiens (human) | ABC-type heme transporter ABCB6,Mitochondrial ABC transporter 3,Mt-ABC transporter 3,P-glycoprotein-related protein,Ubiquitously-expressed mammalian ABC half transporter |
| 2 | C, F (A, B) | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE | non-polymer | 720.0 | 2 | Chemie (PEV) | |||
| 3 | D, G (A, B) | ADP ORTHOVANADATE | non-polymer | 544.2 | 2 | Chemie (AOV) | |||
| 4 | E, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
A, B: 238 - 827 (UniProt: Q9NP58)
| PDB | External Database | Details |
|---|---|---|
| Ala 546 | Trp 546 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 132428.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2576.9 | |
| All* | Total formula weight | 135005.3 |
