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8K7B

post-occluded structure of human ABCB6 W546A mutant (ADP/VO4-bound)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BATP-binding cassette sub-family B member 6polymer59066214.22UniProt (Q9NP58)
Pfam (PF00664)
Pfam (PF00005)
In PDB
Homo sapiens (human)ABC-type heme transporter ABCB6,Mitochondrial ABC transporter 3,Mt-ABC transporter 3,P-glycoprotein-related protein,Ubiquitously-expressed mammalian ABC half transporter
2A, B(1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATEnon-polymer720.02Chemie (PEV)
3A, BADP ORTHOVANADATEnon-polymer544.22Chemie (AOV)
4A, BMAGNESIUM IONnon-polymer24.32Chemie (MG)
Sequence modifications
A, B: 238 - 827 (UniProt: Q9NP58)
PDBExternal DatabaseDetails
Ala 546Trp 546engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight132428.3
Non-Polymers*Number of molecules6
Total formula weight2576.9
All*Total formula weight135005.3
*Water molecules are not included.

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PDB entries from 2024-05-15

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