7ZCW

Cryo-EM structure of GMPCPP-microtubules in complex with VASH2-SVBP

Summary for 7ZCW

• Entry DOI: 10.2210/pdb7zcw/pdb
• EMDB information: 14634
• Descriptor: Tubulin alpha-1B chain, Tubulin beta-2B chain, Tubulinyl-Tyr carboxypeptidase 2, ... (7 entities in total)
• Functional Keywords: microtubule, enzyme, complex, detyrosination, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 352585.91

Authors

Choi, S.R.,Blum, T.,Steinmetz, M.O. (deposition date: 2022-03-29, release date: 2022-12-14, Last modification date: 2023-06-28)

• Primary citation: Ramirez-Rios, S.,Choi, S.R.,Sanyal, C.,Blum, T.B.,Bosc, C.,Krichen, F.,Denarier, E.,Soleilhac, J.M.,Blot, B.,Janke, C.,Stoppin-Mellet, V.,Magiera, M.M.,Arnal, I.,Steinmetz, M.O.,Moutin, M.J.; VASH1-SVBP and VASH2-SVBP generate different detyrosination profiles on microtubules.; J.Cell Biol., 222:-, 2023; PubMed: 36512346; DOI: 10.1083/jcb.202205096

Experimental method

ELECTRON MICROSCOPY (3.6 Å)