4JPZ
Voltage-gated sodium channel 1.2 C-terminal domain in complex with FGF13U and Ca2+/calmodulin
Summary for 4JPZ
Entry DOI | 10.2210/pdb4jpz/pdb |
Related | 4JQ0 |
Descriptor | Fibroblast growth factor 13, Sodium channel protein type 2 subunit alpha, Calmodulin, ... (5 entities in total) |
Functional Keywords | ef hand and iq motif, ion channel, membrane, transport protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cell projection, filopodium . Isoform 1: Nucleus, nucleolus. Isoform 2: Cytoplasm: Q92913 Cell membrane ; Multi-pass membrane protein : Q99250 |
Total number of polymer chains | 6 |
Total formula weight | 119317.00 |
Authors | Wang, C.,Chung, B.C.,Yan, H.,Wang, H.G.,Lee, S.Y.,Pitt, G.S. (deposition date: 2013-03-19, release date: 2014-04-16, Last modification date: 2024-02-28) |
Primary citation | Wang, C.,Chung, B.C.,Yan, H.,Wang, H.G.,Lee, S.Y.,Pitt, G.S. Structural analyses of Ca(2+)/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation. Nat Commun, 5:4896-4896, 2014 Cited by PubMed: 25232683DOI: 10.1038/ncomms5896 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.02 Å) |
Structure validation
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