3I6X
Crystal structure of the calponin homology domain of IQGAP1
Summary for 3I6X
Entry DOI | 10.2210/pdb3i6x/pdb |
Descriptor | Ras GTPase-activating-like protein IQGAP1 (2 entities in total) |
Functional Keywords | all helical, calmodulin-binding, cell membrane, membrane, phosphoprotein, protein binding, membrane protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane : P46940 |
Total number of polymer chains | 4 |
Total formula weight | 89549.76 |
Authors | Kurella, V.B. (deposition date: 2009-07-07, release date: 2010-07-21, Last modification date: 2023-09-06) |
Primary citation | Liu, J.,Kurella, V.B.,LeCour Jr., L.,Vanagunas, T.,Worthylake, D.K. The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin. Biochemistry, 55:6433-6444, 2016 Cited by PubMed: 27798963DOI: 10.1021/acs.biochem.6b00745 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report