3I6X

Crystal structure of the calponin homology domain of IQGAP1

Summary for 3I6X

Entry DOI	10.2210/pdb3i6x/pdb
Descriptor	Ras GTPase-activating-like protein IQGAP1 (2 entities in total)
Functional Keywords	all helical, calmodulin-binding, cell membrane, membrane, phosphoprotein, protein binding, membrane protein
Biological source	Homo sapiens (human)
Cellular location	Cell membrane : P46940
Total number of polymer chains	4
Total formula weight	89549.76
Authors	Kurella, V.B. (deposition date: 2009-07-07, release date: 2010-07-21, Last modification date: 2023-09-06)
Primary citation	Liu, J.,Kurella, V.B.,LeCour Jr., L.,Vanagunas, T.,Worthylake, D.K. The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin. Biochemistry, 55:6433-6444, 2016 Cited by PubMed: 27798963 DOI: 10.1021/acs.biochem.6b00745 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation