1SK6

Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin, 3',5' cyclic AMP (cAMP), and pyrophosphate

Summary for 1SK6

Entry DOI	10.2210/pdb1sk6/pdb
Related	1k90
Descriptor	Calmodulin-sensitive adenylate cyclase, Calmodulin, YTTERBIUM (III) ION, ... (6 entities in total)
Functional Keywords	ef3 camp ppi cam, toxin, lyase-metal binding protein complex, lyase/metal binding protein
Biological source	Bacillus anthracis More
Total number of polymer chains	6
Total formula weight	229909.19
Authors	Guo, Q.,Shen, Y.,Zhukovskaya, N.L.,Tang, W.J. (deposition date: 2004-03-04, release date: 2004-06-08, Last modification date: 2023-08-23)
Primary citation	Guo, Q.,Shen, Y.,Zhukovskaya, N.L.,Florian, J.,Tang, W.J. Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate. J.Biol.Chem., 279:29427-29435, 2004 Cited by PubMed: 15131111 DOI: 10.1074/jbc.M402689200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation