1SK6
Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin, 3',5' cyclic AMP (cAMP), and pyrophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, B, C) | Calmodulin-sensitive adenylate cyclase | polymer | 510 | 58810.6 | 3 | UniProt (P40136) Pfam (PF03497) Pfam (PF20850) | Bacillus anthracis | ATP pyrophosphate-lyase, Adenylyl cyclase, Edema factor, EF, Anthrax edema toxin adenylate cyclase component |
| 2 | B, D, F (D, E, F) | Calmodulin | polymer | 148 | 16721.3 | 3 | UniProt (P02593) Pfam (PF13499) UniProt (by SIFTS) (P0DP23) | Homo sapiens (human) | |
| 3 | G, H, I, N, O... (A, B, C) | YTTERBIUM (III) ION | non-polymer | 173.0 | 9 | Chemie (YB) | |||
| 4 | J, Q, X (A, B, C) | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 3 | Chemie (CMP) | |||
| 5 | K, R, Y (A, B, C) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 3 | Chemie (POP) | |||
| 6 | AA, L, M, S, T... (F, D, E) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 226595.9 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 3313.3 | |
| All* | Total formula weight | 229909.2 |
