1SK6
Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin, 3',5' cyclic AMP (cAMP), and pyrophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, B, C) | Calmodulin-sensitive adenylate cyclase | polymer | 510 | 58810.6 | 3 | UniProt (P40136) Pfam (PF03497) Pfam (PF20850) | Bacillus anthracis | ATP pyrophosphate-lyase, Adenylyl cyclase, Edema factor, EF, Anthrax edema toxin adenylate cyclase component |
| 2 | B, D, F (D, E, F) | Calmodulin | polymer | 148 | 16721.3 | 3 | UniProt (P02593) Pfam (PF13499) UniProt (by SIFTS) (P0DP23) | Homo sapiens (human) | |
| 3 | G, H, I, N, O... (A, B, C) | YTTERBIUM (III) ION | non-polymer | 173.0 | 9 | Chemie (YB) PubChem (105055) | |||
| 4 | J, Q, X (A, B, C) | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 3 | Chemie (CMP) PubChem (6076) PubChem (176488666) PubChem (216878) PubChem (23902375) PubChem (25322948) PubChem (40467852) PubChem (44629928) PubChem (25322946) PubChem (3080770) PubChem (56973690) PubChem (3246347) PubChem (59909322) PubChem (59968988) PubChem (59350541) PubChem (70878457) PubChem (274) PubChem (6603718) PubChem (6713792) PubChem (6714006) PubChem (12071879) PubChem (12866365) PubChem (6604194) PubChem (124132380) PubChem (129317551) PubChem (131841987) PubChem (134693155) PubChem (163043517) PubChem (138107790) PubChem (163043518) | |||
| 5 | K, R, Y (A, B, C) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 3 | Chemie (POP) PubChem (4995) | |||
| 6 | AA, L, M, S, T... (F, D, E) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) PubChem (271) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 226595.9 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 3313.3 | |
| All* | Total formula weight | 229909.2 |
