7ZEK
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7ZUR
| Four carbons pendant pyridine derivative of the natural alkaloid Berberine as Human Telomeric G-quadruplex Binder | Descriptor: | 16,17-dimethoxy-21-(4-pyridin-4-ylbutyl)-5,7-dioxa-13$l^{4}-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2(10),3,8,13,15,17,19-octaene, DNA TAGGGTTAGGGT, POTASSIUM ION | Authors: | Bazzicalupi, C, Ferraroni, M, Gratteri, P, Papi, F. | Deposit date: | 2022-05-13 | Release date: | 2022-12-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Probing the Efficiency of 13-Pyridylalkyl Berberine Derivatives to Human Telomeric G-Quadruplexes Binding: Spectroscopic, Solid State and In Silico Analysis. Int J Mol Sci, 23, 2022
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8AAD
| Two carbons pendant pyridine derivative of the natural alkaloid Berberine as Human Telomeric G-quadruplex Binder | Descriptor: | 16,17-dimethoxy-21-(2-pyridin-4-ylethyl)-5,7-dioxa-13$l^{4}-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(13),2,4(8),9,14,16,18,20-octaene, DNA TAGGGTTAGGGT, POTASSIUM ION | Authors: | Ferraroni, M, Bazzicalupi, C, Gratteri, P, Papi, F. | Deposit date: | 2022-07-01 | Release date: | 2022-12-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Probing the Efficiency of 13-Pyridylalkyl Berberine Derivatives to Human Telomeric G-Quadruplexes Binding: Spectroscopic, Solid State and In Silico Analysis. Int J Mol Sci, 23, 2022
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2MB2
| parallel-stranded G-quadruplex in DNA poly-G stretches | Descriptor: | DNA_(5'-D(*TP*TP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*T)-3') | Authors: | Sengar, A, Heddi, B, Phan, A.T. | Deposit date: | 2013-07-24 | Release date: | 2014-12-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Formation of g-quadruplexes in poly-g sequences: structure of a propeller-type parallel-stranded g-quadruplex formed by a g15 stretch. Biochemistry, 53, 2014
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2JPZ
| Human telomere DNA quadruplex structure in K+ solution hybrid-2 form | Descriptor: | DNA (26-MER) | Authors: | Dai, J, Carver, M, Punchihewa, C, Jones, R, Yang, D. | Deposit date: | 2007-05-25 | Release date: | 2007-12-04 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence Nucleic Acids Res., 35, 2007
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2AWE
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2MB3
| Solution structure of an intramolecular (3+1) human telomeric G-quadruplex bound to a telomestatin derivative | Descriptor: | (12S,27S)-12,27-bis(4-aminobutyl)-4,30-dimethyl-3,7,14,18,22,29-hexaoxa-11,26,31,32,33,34,35,36-octaazaheptacyclo[26.2. 1.1~2,5~.1~6,9~.1~13,16~.1~17,20~.1~21,24~]hexatriaconta-1(30),2(36),4,6(35),8,13(34),15,17(33),19,21(32),23,28(31)-dode caene-10,25-dione, DNA_(5'-D(*TP*TP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*A)-3') | Authors: | Chung, W.J, Heddi, B, Tera, M, Iida, K, Nagasawa, K, Phan, A.T. | Deposit date: | 2013-07-24 | Release date: | 2013-08-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of an intramolecular (3 + 1) human telomeric g-quadruplex bound to a telomestatin derivative. J.Am.Chem.Soc., 135, 2013
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2L7V
| Quindoline/G-quadruplex complex | Descriptor: | DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3'), N,N-diethyl-N'-(10H-indolo[3,2-b]quinolin-11-yl)ethane-1,2-diamine, POTASSIUM ION | Authors: | Dai, J, Carver, M, Mathad, R, Yang, D. | Deposit date: | 2010-12-23 | Release date: | 2011-11-09 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution Structure of a 2:1 Quindoline-c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design. J.Am.Chem.Soc., 133, 2011
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2KYO
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2KYP
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2MB4
| Solution structure of a stacked dimeric G-quadruplex formed by a segment of the human CEB1 minisatellite | Descriptor: | DNA_(5'-D(*AP*GP*GP*GP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*TP*GP*G)-3') | Authors: | Adrian, M, Ang, D.J, Lech, C, Heddi, B, Nicolas, A, Phan, A.T. | Deposit date: | 2013-07-25 | Release date: | 2014-05-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and Conformational Dynamics of a Stacked Dimeric G-Quadruplex Formed by the Human CEB1 Minisatellite. J.Am.Chem.Soc., 136, 2014
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2KF7
| Structure of a two-G-tetrad basket-type intramolecular G-quadruplex formed by human telomeric repeats in K+ solution (with G7-to-BRG substitution) | Descriptor: | HUMAN TELOMERE DNA | Authors: | Lim, K.W, Amrane, S, Bouaziz, S, Xu, W, Mu, Y, Patel, D.J, Luu, K.N, Phan, A.T. | Deposit date: | 2009-02-12 | Release date: | 2009-03-24 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers J.Am.Chem.Soc., 131, 2009
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2KF8
| Structure of a two-G-tetrad basket-type intramolecular G-quadruplex formed by human telomeric repeats in K+ solution | Descriptor: | HUMAN TELOMERE DNA | Authors: | Lim, K.W, Amrane, S, Bouaziz, S, Xu, W, Mu, Y, Patel, D.J, Luu, K.N, Phan, A.T. | Deposit date: | 2009-02-12 | Release date: | 2009-03-24 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers J.Am.Chem.Soc., 131, 2009
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7E5P
| Aptamer enhancing peroxidase activity of myoglobin | Descriptor: | DNA (5'-D(*GP*GP*GP*TP*GP*GP*GP*TP*TP*GP*GP*GP*AP*GP*GP*G)-3') | Authors: | Tsukakoshi, K, Matsugami, A, Khunathai, K, Kanazashi, M, Yamagishi, Y, Nakama, K, Oshikawa, D, Hayashi, F, Kuno, H, Ikebukuro, K. | Deposit date: | 2021-02-19 | Release date: | 2021-06-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | G-quadruplex-forming aptamer enhances the peroxidase activity of myoglobin against luminol. Nucleic Acids Res., 49, 2021
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7DO1
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2M18
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2LED
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2LEE
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2KBP
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2KZD
| Structure of a (3+1) G-quadruplex formed by hTERT promoter sequence | Descriptor: | DNA (5'-D(*AP*GP*GP*GP*IP*AP*GP*GP*GP*GP*CP*TP*GP*GP*GP*AP*GP*GP*GP*C)-3') | Authors: | Lim, K.W, Lacroix, L, Yue, D.J.E, Lim, J.K.C, Lim, J.M.W, Phan, A.T. | Deposit date: | 2010-06-16 | Release date: | 2010-10-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Coexistence of two distinct G-quadruplex conformations in the hTERT promoter J.Am.Chem.Soc., 132, 2010
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2KZE
| Structure of an all-parallel-stranded G-quadruplex formed by hTERT promoter sequence | Descriptor: | DNA (5'-D(*AP*IP*GP*GP*GP*AP*GP*GP*GP*IP*CP*TP*GP*GP*GP*AP*GP*GP*GP*C)-3') | Authors: | Lim, K.W, Lacroix, L, Yue, D.J.E, Lim, J.K.C, Lim, J.M.W, Phan, A.T. | Deposit date: | 2010-06-16 | Release date: | 2010-10-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Coexistence of two distinct G-quadruplex conformations in the hTERT promoter J.Am.Chem.Soc., 132, 2010
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2LE6
| Structure of a dimeric all-parallel-stranded G-quadruplex stacked via the 5'-to-5' interface | Descriptor: | DNA (5'-D(*GP*IP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3') | Authors: | Do, N.Q, Lim, K.W, Teo, M.H, Heddi, B, Phan, A.T. | Deposit date: | 2011-06-10 | Release date: | 2011-08-31 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Stacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activity Nucleic Acids Res., 2011
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2LXV
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2LXQ
| Monomeric PilE G-Quadruplex DNA from Neisseria Gonorrhoeae | Descriptor: | DNA (5'-D(*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*TP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*T)-3') | Authors: | Kuryavyi, V.V, Patel, D.J. | Deposit date: | 2012-08-30 | Release date: | 2012-11-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | RecA-Binding pilE G4 Sequence Essential for Pilin Antigenic Variation Forms Monomeric and 5' End-Stacked Dimeric Parallel G-Quadruplexes. Structure, 20, 2012
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2LA5
| RNA Duplex-Quadruplex Junction Complex with FMRP RGG peptide | Descriptor: | Fragile X mental retardation 1 protein, RNA (36-MER) | Authors: | Phan, A, Kuryavyi, V, Darnell, J, Serganov, A, Majumdar, A, Ilin, S, Darnell, R, Patel, D. | Deposit date: | 2011-03-03 | Release date: | 2011-06-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction. Nat.Struct.Mol.Biol., 18, 2011
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