2L7V

Quindoline/G-quadruplex complex

Summary for 2L7V

• Entry DOI: 10.2210/pdb2l7v/pdb
• NMR Information: BMRB: 17379
• Descriptor: DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3'), POTASSIUM ION, N,N-diethyl-N'-(10H-indolo[3,2-b]quinolin-11-yl)ethane-1,2-diamine (3 entities in total)
• Functional Keywords: c-myc promoter, dna-inhibitor complex, c-myc promoter g-quadruplex, dna/inhibitor
• Total number of polymer chains: 1
• Total formula weight: 7751.59

Authors

Dai, J.,Carver, M.,Mathad, R.,Yang, D. (deposition date: 2010-12-23, release date: 2011-11-09, Last modification date: 2011-11-16)

• Primary citation: Dai, J.,Carver, M.,Hurley, L.H.,Yang, D.; Solution Structure of a 2:1 Quindoline-c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design.; J.Am.Chem.Soc., 133:17673-17680, 2011; PubMed: 21967482; DOI: 10.1021/ja205646q

Experimental method

SOLUTION NMR