2KZD

Structure of a (3+1) G-quadruplex formed by hTERT promoter sequence

Summary for 2KZD

• Entry DOI: 10.2210/pdb2kzd/pdb
• Related: 2A5P 2KZE 2O3M
• Descriptor: DNA (5'-D(*AP*GP*GP*GP*IP*AP*GP*GP*GP*GP*CP*TP*GP*GP*GP*AP*GP*GP*GP*C)-3') (1 entity in total)
• Functional Keywords: anticancer targets, g-quadruplex, htert promoter, telomerase inhibition, dna
• Total number of polymer chains: 1
• Total formula weight: 6371.09

Authors

Lim, K.W.,Lacroix, L.,Yue, D.J.E.,Lim, J.K.C.,Lim, J.M.W.,Phan, A.T. (deposition date: 2010-06-16, release date: 2010-10-06, Last modification date: 2011-07-13)

• Primary citation: Lim, K.W.,Lacroix, L.,Yue, D.J.E.,Lim, J.K.C.,Lim, J.M.W.,Phan, A.T.; Coexistence of two distinct G-quadruplex conformations in the hTERT promoter; J.Am.Chem.Soc., 132:12331-12342, 2010; PubMed: 20704263; DOI: 10.1021/ja101252n

Experimental method

SOLUTION NMR