2KF8

Structure of a two-G-tetrad basket-type intramolecular G-quadruplex formed by human telomeric repeats in K+ solution

Summary for 2KF8

Related143D 1K8P 2GKU 2AQY 2JSK 2JSL 2JSM 2JSQ 2KF7
DescriptorHUMAN TELOMERE DNA (1 entity in total)
Functional Keywordsanticancer targets, human telomere, intramolecular g-quadruplexes, dna
Total number of polymer chains1
Total molecular weight6974.48
Authors
Lim, K.W.,Amrane, S.,Bouaziz, S.,Xu, W.,Mu, Y.,Patel, D.J.,Luu, K.N.,Phan, A.T. (deposition date: 2009-02-12, release date: 2009-03-24, Last modification date: 2011-07-13)
Primary citation
Lim, K.W.,Amrane, S.,Bouaziz, S.,Xu, W.,Mu, Y.,Patel, D.J.,Luu, K.N.,Phan, A.T.
Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers
J.Am.Chem.Soc., 131:4301-4309, 2009
PubMed: 19271707 (PDB entries with the same primary citation)
DOI: 10.1021/ja807503g
MImport into Mendeley
Experimental method
SOLUTION NMR
?

Structure validation

Clashscore19MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 2kf8
no rotation
Molmil generated image of 2kf8
rotated about x axis by 90°
Molmil generated image of 2kf8
rotated about y axis by 90°