2KF7

Structure of a two-G-tetrad basket-type intramolecular G-quadruplex formed by human telomeric repeats in K+ solution (with G7-to-BRG substitution)

Summary for 2KF7

Related143D 1K8P 2GKU 2AQY 2JSK 2JSL 2JSM 2JSQ 2KF8
DescriptorHUMAN TELOMERE DNA (1 entity in total)
Functional Keywordsanticancer targets, human telomere, intramolecular g-quadruplexes, dna
Total number of polymer chains1
Total molecular weight7053.38
Authors
Lim, K.W.,Amrane, S.,Bouaziz, S.,Xu, W.,Mu, Y.,Patel, D.J.,Luu, K.N.,Phan, A.T. (deposition date: 2009-02-12, release date: 2009-03-24, Last modification date: 2011-07-13)
Primary citation
Lim, K.W.,Amrane, S.,Bouaziz, S.,Xu, W.,Mu, Y.,Patel, D.J.,Luu, K.N.,Phan, A.T.
Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers
J.Am.Chem.Soc., 131:4301-4309, 2009
PubMed: 19271707 (PDB entries with the same primary citation)
DOI: 10.1021/ja807503g
MImport into Mendeley
Experimental method
SOLUTION NMR
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Structure validation

Clashscore16MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 2kf7
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Molmil generated image of 2kf7
rotated about x axis by 90°
Molmil generated image of 2kf7
rotated about y axis by 90°