PDB: 1828 件ウェブページステータス検索Chemie searchBIRD

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2ZFX	Crystal structure of the rat vitamin D receptor ligand binding domain complexed with YR301 and a synthetic peptide containing the NR2 box of DRIP 205 分子名称: (2S)-3-{4-[1-ethyl-1-(4-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}-3-methylphenyl)propyl]-2-methylphenoxy}propane-1,2-diol, DRIP 205 NR2 box peptide, Vitamin D3 receptor 著者 Kakuda, S, Takimoto-Kamimura, M. 登録日 2008-01-15 公開日 2009-01-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structure of the ligand-binding domain of rat VDR in complex with the nonsecosteroidal vitamin D3 analogue YR301 Acta Crystallogr.,Sect.F, 64, 2008
2ZBS	Crystal structure of human estrogen-related receptor gamma ligand binding domain apo form 分子名称: Estrogen-related receptor gamma 著者 Matsushima, A, Kakuta, Y, Teramoto, T, Shimohigashi, Y. 登録日 2007-10-27 公開日 2008-10-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 ERRgamma tethers strongly bisphenol A and 4-alpha-cumylphenol in an induced-fit manner Biochem.Biophys.Res.Commun., 373, 2008
2ZAS	Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with 4-alpha-cumylphenol, a bisphenol A derivative 分子名称: 4-(1-methyl-1-phenylethyl)phenol, Estrogen-related receptor gamma, GLYCEROL 著者 Matsushima, A, Kakuta, Y, Teramoto, T, Shimohigashi, Y. 登録日 2007-10-09 公開日 2008-10-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 ERRgamma tethers strongly bisphenol A and 4-alpha-cumylphenol in an induced-fit manner Biochem.Biophys.Res.Commun., 373, 2008
2Z4J	Crystal structure of AR LBD with SHP peptide NR Box 2 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor 0B2 著者 Jouravel, N, Fletterick, R.J. 登録日 2007-06-19 公開日 2007-12-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Interaction between the androgen receptor and a segment of its corepressor SHP Acta Crystallogr.,Sect.D, 63, 2007
2Z4B	Estrogen receptor beta ligand-binding domain complexed to a benzopyran ligand 分子名称: (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL, Estrogen receptor beta 著者 Wang, Y. 登録日 2007-06-14 公開日 2007-08-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 3: Synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification. Bioorg.Med.Chem.Lett., 17, 2007
2YLY	Sulfonamides as selective Estrogen Receptor beta Agonists. 分子名称: ESTROGEN RECEPTOR BETA, N-cyclopropyl-4-oxidanyl-N-[(2R)-2-oxidanyl-2-phenyl-propyl]benzenesulfonamide, SULFATE ION 著者 Roberts, L.R, Armour, D, Barker, C, Bazin, R, Bess, K, Brown, A, Favor, D, Ellis, D, MacKenny, M, Pullen, N, Stennett, A, Strand, L, Styles, M, Phillips, C. 登録日 2011-06-06 公開日 2012-06-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Sulfonamides as Selective Oestrogen Receptor Beta Agonists. Bioorg.Med.Chem.Lett., 21, 2011
2YLQ	TARGETING THE BINDING FUNCTION 3 SITE OF THE ANDROGEN RECEPTOR THROUGH IN SILICO MOLECULAR MODELING 分子名称: 3-[1-[2-(4-METHYLPHENOXY)ETHYL]BENZIMIDAZOL-2-YL]SULFANYLPROPANOIC ACID, ANDROGEN RECEPTOR, SULFATE ION, ... 著者 Lack, N.A, Axerio, P, Tavassoli, P, Kuchenbecker, K, Han, F.Q, Chan, K.H, Feau, C, LeBlanc, E, Tomlinson, E, Guy, R.K, Rennie, P.S, Cherkasov, A. 登録日 2011-06-04 公開日 2011-07-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Targeting the Binding Function 3 (Bf3) Site of the Human Androgen Receptor Through Virtual Screening. J.Med.Chem., 54, 2011
2YLP	TARGETING THE BINDING FUNCTION 3 SITE OF THE ANDROGEN RECEPTOR THROUGH IN SILICO MOLECULAR MODELING 分子名称: 3-[(2,4-DICHLOROPHENYL)METHYLSULFANYLMETHYL]BENZOIC ACID, ANDROGEN RECEPTOR, SULFATE ION, ... 著者 Lack, N.A, Axerio, P, Tavassoli, P, Kuchenbecker, K, Han, F.Q, Chan, K.H, Feau, C, LeBlanc, E, Tomlinson, E, Guy, R.K, Rennie, P.S, Cherkasov, A. 登録日 2011-06-04 公開日 2011-07-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Targeting the Binding Function 3 (Bf3) Site of the Human Androgen Receptor Through Virtual Screening. J.Med.Chem., 54, 2011
2YLO	TARGETING THE BINDING FUNCTION 3 SITE OF THE ANDROGEN RECEPTOR THROUGH IN SILICO MOLECULAR MODELING 分子名称: 1-[2-(4-METHYLPHENOXY)ETHYL]-2-(2-PHENOXYETHYLSULFANYL)BENZIMIDAZOLE, ANDROGEN RECEPTOR, SULFATE ION, ... 著者 Lack, N.A, Axerio, P, Tavassoli, P, Kuchenbecker, K, Han, F.Q, Chan, K.H, Feau, C, LeBlanc, E, Tomlinson, E, Guy, R.K, Rennie, P.S, Cherkasov, A. 登録日 2011-06-04 公開日 2011-07-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Targeting the Binding Function 3 (Bf3) Site of the Human Androgen Receptor Through Virtual Screening. J.Med.Chem., 54, 2011
2YJD	Stapled peptide bound to Estrogen Receptor Beta 分子名称: 4-(2-PROPAN-2-YLOXYBENZIMIDAZOL-1-YL)PHENOL, ESTROGEN RECEPTOR BETA, STAPLED PEPTIDE 著者 Phillips, C, Roberts, L.R, Schade, M, Bent, A, Davies, N.L, Moore, R, Pannifer, A.D, Brown, D.G, Pickford, A.R, Irving, S.L. 登録日 2011-05-19 公開日 2011-08-03 最終更新日 2017-01-25 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Design and Structure of Stapled Peptides Binding to Estrogen Receptors. J.Am.Chem.Soc., 133, 2011
2YJA	Stapled Peptides binding to Estrogen Receptor alpha. 分子名称: ESTRADIOL, ESTROGEN RECEPTOR, STAPLED PEPTIDE 著者 Phillips, C, Roberts, L.R, Schade, M, Bazin, R, Bent, A, Davies, N.L, Irving, S.L, Moore, R, Pannifer, A.D, Brown, D.G, Pickford, A.R, Scott, A, Xu, B. 登録日 2011-05-19 公開日 2011-08-03 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Design and Structure of Stapled Peptides Binding to Estrogen Receptors. J.Am.Chem.Soc., 133, 2011
2YHD	Human androgen receptor in complex with AF2 small molecule inhibitor 分子名称: 4-(2,3-dihydro-1H-perimidin-2-yl)benzene-1,2-diol, ANDROGEN RECEPTOR, SULFATE ION, ... 著者 AxerioCilies, P, Lack, N.A, ShashiNayana, M.R, Chan, K.H, Yeung, A, LeBlanc, E, Guns, E, Rennie, P, Cherkasov, A. 登録日 2011-04-28 公開日 2011-09-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Inhibitors of Androgen Receptor Activation Function-2 (Af2) Site Identified Through Virtual Screening. J.Med.Chem., 54, 2011
2YFE	Ligand binding domain of human PPAR gamma in complex with amorfrutin 1 分子名称: Amorfrutin 1, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA 著者 de Groot, J.C, Buessow, K. 登録日 2011-04-05 公開日 2012-04-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Amorfrutins are Potent Antidiabetic Dietary Natural Products Proc.Natl.Acad.Sci.USA, 109, 2012
2YAT	Crystal structure of estradiol derived metal chelate and estrogen receptor-ligand binding domain complex 分子名称: ESTRADIOL-PYRIDINIUM TETRAACETIC ACID, ESTROGEN RECEPTOR, EUROPIUM ION, ... 著者 Li, M.J, Greenblatt, H.M, Dym, O, Albeck, S, Degani, H, Sussman, J.L. 登録日 2011-02-24 公開日 2011-06-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.602 Å) 主引用文献 Structure of Estradiol Metal Chelate and Estrogen Receptor Complex: The Basis for Designing a New Class of Selective Estrogen Receptor Modulators. J.Med.Chem., 54, 2011
2XYX	Novel Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator-Activated Receptor (PPAR) gamma-delta Agonists with High Potency and In-vivo Efficacy 分子名称: 4-[2-[[3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]AMINO]ETHYL]-N-(5-PROPAN-2-YL-1,3,4-THIADIAZOL-2-YL)BENZENESULFONAMIDE, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA, octyl beta-D-glucopyranoside 著者 Marquette, J.-P, Mathieu, M. 登録日 2010-11-19 公開日 2011-02-23 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator-Activated Receptor (Ppar) Gamma / Delta Agonists with High Potency and in-Vivo Efficacy Chemmedchem, 6, 2011
2XYW	Novel Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator-Activated Receptor (PPAR) gamma-delta Agonists with High Potency and In-vivo Efficacy 分子名称: 3-CHLORO-6-FLUORO-N-[2-[4-[(5-PROPAN-2-YL-1,3,4-THIADIAZOL-2-YL)SULFAMOYL]PHENYL]ETHYL]-1-BENZOTHIOPHENE-2-CARBOXAMIDE, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA, octyl beta-D-glucopyranoside 著者 Marquette, J.-P, Mathieu, M. 登録日 2010-11-19 公開日 2011-02-23 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator-Activated Receptor (Ppar) Gamma / Delta Agonists with High Potency and in-Vivo Efficacy Chemmedchem, 6, 2011
2XYJ	Novel Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator-Activated Receptor (PPAR) gamma-delta Agonists with High Potency and In-vivo Efficacy 分子名称: 5-CHLORO-2-METHOXY-N-[2-[4-[(5-PROPAN-2-YL-1,3,4-THIADIAZOL-2-YL)SULFAMOYL]PHENYL]ETHYL]BENZAMIDE, PENTAETHYLENE GLYCOL, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA 著者 Marquette, J.-P, Mathieu, M. 登録日 2010-11-18 公開日 2011-02-23 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator-Activated Receptor (Ppar) Gamma / Delta Agonists with High Potency and in-Vivo Efficacy Chemmedchem, 6, 2011
2XKW	LIGAND BINDING DOMAIN OF HUMAN PPAR-GAMMA IN COMPLEX WITH THE AGONIST PIOGLITAZONE 分子名称: (5R)-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Mueller, J.J, Schupp, M, Unger, T, Kintscher, U, Heinemann, U. 登録日 2010-07-14 公開日 2011-08-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Binding Diversity of Pioglitazone by Peroxisome Proliferator-Activated Receptor-Gamma To be Published
2XHS	Crystal structure of the ligand binding domain of Fushi tarazu factor 1 of Drosophila melanogaster. 分子名称: NUCLEAR HORMONE RECEPTOR FTZ-F1, SEGMENTATION PROTEIN FUSHI TARAZU 著者 Yoo, J.H, Cho, H.S. 登録日 2010-06-21 公開日 2011-07-20 最終更新日 2018-06-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of Fushi Tarazu Factor 1 Ligand Binding Domain/Fushi Tarazu Peptide Complex Identifies New Class of Nuclear Receptors. J.Biol.Chem., 286, 2011
2W8Y	RU486 bound to the progesterone receptor in a destabilized agonistic conformation 分子名称: (14beta,17alpha)-17-ethynyl-17-hydroxyestr-4-en-3-one, 1,2-ETHANEDIOL, 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, ... 著者 Raaijmakers, H.C.A, Versteeg, J, Uitdehaag, J.C.M. 登録日 2009-01-20 公開日 2009-04-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The X-Ray Structure of Ru486 Bound to the Progesterone Receptor in a Destabilized Agonistic Conformation. J.Biol.Chem., 284, 2009
2VV4	hPPARgamma Ligand binding domain in complex with 6-oxoOTE 分子名称: (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid, (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA 著者 Itoh, T, Fairall, L, Schwabe, J.W.R. 登録日 2008-06-02 公開日 2008-08-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural Basis for the Activation of Pparg by Oxidised Fatty Acids Nat.Struct.Mol.Biol., 15, 2008
2VV3	hPPARgamma Ligand binding domain in complex with 4-oxoDHA 分子名称: (6E,10Z,13Z,16Z,19Z)-4-oxodocosa-6,10,13,16,19-pentaenoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA 著者 Itoh, T, Fairall, L, Schwabe, J.W.R. 登録日 2008-06-02 公開日 2008-08-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structural Basis for the Activation of Ppargamma by Oxidized Fatty Acids. Nat.Struct.Mol.Biol., 15, 2008
2VV2	hPPARgamma Ligand binding domain in complex with 5-HEPA 分子名称: (5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA 著者 Itoh, T, Fairall, L, Schwabe, J.W.R. 登録日 2008-06-02 公開日 2008-08-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural Basis for the Activation of Pparg by Oxidised Fatty Acids Nat.Struct.Mol.Biol., 15, 2008
2VV1	hPPARgamma Ligand binding domain in complex with 4-HDHA 分子名称: (4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA 著者 Itoh, T, Fairall, L, Schwabe, J.W.R. 登録日 2008-06-02 公開日 2008-08-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis for the Activation of Pparg by Oxidised Fatty Acids Nat.Struct.Mol.Biol., 15, 2008
2VV0	hPPARgamma Ligand binding domain in complex with DHA 分子名称: DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA 著者 Itoh, T, Fairall, L, Schwabe, J.W.R. 登録日 2008-06-02 公開日 2008-08-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural Basis for the Activation of Pparg by Oxidised Fatty Acids Nat.Struct.Mol.Biol., 15, 2008

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