2XYJ
Novel Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator-Activated Receptor (PPAR) gamma-delta Agonists with High Potency and In-vivo Efficacy
Summary for 2XYJ
Entry DOI | 10.2210/pdb2xyj/pdb |
Related | 1GWX 1Y0S 2AWH 2B50 2BAW 2GWX 2J14 2XYW 2XYX 3GWX |
Descriptor | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA, 5-CHLORO-2-METHOXY-N-[2-[4-[(5-PROPAN-2-YL-1,3,4-THIADIAZOL-2-YL)SULFAMOYL]PHENYL]ETHYL]BENZAMIDE, PENTAETHYLENE GLYCOL, ... (4 entities in total) |
Functional Keywords | transcription |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 68210.83 |
Authors | Marquette, J.-P.,Mathieu, M. (deposition date: 2010-11-18, release date: 2011-02-23, Last modification date: 2024-05-01) |
Primary citation | Keil, S.,Matter, H.,Schonafinger, K.,Glien, M.,Mathieu, M.,Marquette, J.-P.,Michot, N.,Haag-Diergarten, S.,Urmann, M.,Wendler, W. Sulfonylthiadiazoles with an Unusual Binding Mode as Partial Dual Peroxisome Proliferator-Activated Receptor (Ppar) Gamma / Delta Agonists with High Potency and in-Vivo Efficacy Chemmedchem, 6:633-, 2011 Cited by PubMed: 21400663DOI: 10.1002/CMDC.201100047 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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