2ZAS

Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with 4-alpha-cumylphenol, a bisphenol A derivative

Summary for 2ZAS

Entry DOI	10.2210/pdb2zas/pdb
Related	2E2R
Descriptor	Estrogen-related receptor gamma, 4-(1-methyl-1-phenylethyl)phenol, GLYCEROL, ... (4 entities in total)
Functional Keywords	err gamma, bpa, 4-alpha-cumylphenol, nuclear receptor, transcription, activator, dna-binding, metal-binding, nucleus, transcription regulation, zinc-finger
Biological source	Homo sapiens (human)
Cellular location	Nucleus : P62508
Total number of polymer chains	1
Total formula weight	27915.52
Authors	Matsushima, A.,Kakuta, Y.,Teramoto, T.,Shimohigashi, Y. (deposition date: 2007-10-09, release date: 2008-10-07, Last modification date: 2023-11-01)
Primary citation	Matsushima, A.,Teramoto, T.,Okada, H.,Liu, X.,Tokunaga, T.,Kakuta, Y.,Shimohigashi, Y. ERRgamma tethers strongly bisphenol A and 4-alpha-cumylphenol in an induced-fit manner Biochem.Biophys.Res.Commun., 373:408-413, 2008 Cited by PubMed: 18582436 DOI: 10.1016/j.bbrc.2008.06.050 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation