2YLY
Sulfonamides as selective Estrogen Receptor beta Agonists.
Summary for 2YLY
Entry DOI | 10.2210/pdb2yly/pdb |
Related | 1L2J 1NDE 1QKM 1U3Q 1U3R 1U3S 1U9E 1X76 1X78 1X7B 1X7J 1YY4 1YYE 2FSZ 2JJ3 |
Descriptor | ESTROGEN RECEPTOR BETA, N-cyclopropyl-4-oxidanyl-N-[(2R)-2-oxidanyl-2-phenyl-propyl]benzenesulfonamide, SULFATE ION (3 entities in total) |
Functional Keywords | receptor |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus: Q92731 |
Total number of polymer chains | 2 |
Total formula weight | 55189.43 |
Authors | Roberts, L.R.,Armour, D.,Barker, C.,Bazin, R.,Bess, K.,Brown, A.,Favor, D.,Ellis, D.,MacKenny, M.,Pullen, N.,Stennett, A.,Strand, L.,Styles, M.,Phillips, C. (deposition date: 2011-06-06, release date: 2012-06-13, Last modification date: 2024-05-08) |
Primary citation | Roberts, L.R.,Armor, D.,Barker, C.,Bent, A.,Bess, K.,Brown, A.,Favor, D.A.,Ellis, D.,Irving, S.L.,Mackenny, M.,Phillips, C.,Pullen, N.,Stennett, A.,Strand, L.,Styles, M. Sulfonamides as Selective Oestrogen Receptor Beta Agonists. Bioorg.Med.Chem.Lett., 21:5680-, 2011 Cited by PubMed: 21885279DOI: 10.1016/J.BMCL.2011.08.041 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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