2YLY

Sulfonamides as selective Estrogen Receptor beta Agonists.

Summary for 2YLY

Entry DOI	10.2210/pdb2yly/pdb
Related	1L2J 1NDE 1QKM 1U3Q 1U3R 1U3S 1U9E 1X76 1X78 1X7B 1X7J 1YY4 1YYE 2FSZ 2JJ3
Descriptor	ESTROGEN RECEPTOR BETA, N-cyclopropyl-4-oxidanyl-N-[(2R)-2-oxidanyl-2-phenyl-propyl]benzenesulfonamide, SULFATE ION (3 entities in total)
Functional Keywords	receptor
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus: Q92731
Total number of polymer chains	2
Total formula weight	55189.43
Authors	Roberts, L.R.,Armour, D.,Barker, C.,Bazin, R.,Bess, K.,Brown, A.,Favor, D.,Ellis, D.,MacKenny, M.,Pullen, N.,Stennett, A.,Strand, L.,Styles, M.,Phillips, C. (deposition date: 2011-06-06, release date: 2012-06-13, Last modification date: 2024-05-08)
Primary citation	Roberts, L.R.,Armor, D.,Barker, C.,Bent, A.,Bess, K.,Brown, A.,Favor, D.A.,Ellis, D.,Irving, S.L.,Mackenny, M.,Phillips, C.,Pullen, N.,Stennett, A.,Strand, L.,Styles, M. Sulfonamides as Selective Oestrogen Receptor Beta Agonists. Bioorg.Med.Chem.Lett., 21:5680-, 2011 Cited by PubMed: 21885279 DOI: 10.1016/J.BMCL.2011.08.041 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation