1NDE

Estrogen Receptor beta with Selective Triazine Modulator

Summary for 1NDE

Entry DOI	10.2210/pdb1nde/pdb
Descriptor	Estrogen receptor beta, 4-(2-{[4-{[3-(4-CHLOROPHENYL)PROPYL]SULFANYL}-6-(1-PIPERAZINYL)-1,3,5-TRIAZIN-2-YL]AMINO}ETHYL)PHENOL (3 entities in total)
Functional Keywords	estrogen receptor, estrogen receptor beta, er, erb, triazine, estrogen, estradiol, oestrogen, transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q92731
Total number of polymer chains	1
Total formula weight	29595.60
Authors	Henke, B.R.,Consler, T.G.,Go, N.,Hale, R.L.,Hohman, D.R.,Jones, S.A.,Lu, A.T.,Moore, L.B.,Moore, J.T.,Orband-Miller, L.A.,Robinett, R.G.,Shearin, J.,Spearing, P.K.,Stewart, E.L.,Turnbull, P.S.,Weaver, S.L.,Williams, S.P.,Wisely, G.B.,Lambert, M.H. (deposition date: 2002-12-09, release date: 2002-12-18, Last modification date: 2023-08-16)
Primary citation	Henke, B.R.,Consler, T.G.,Go, N.,Hale, R.L.,Hohman, D.R.,Jones, S.A.,Lu, A.T.,Moore, L.B.,Moore, J.T.,Orband-Miller, L.A.,Robinett, R.G.,Shearin, J.,Spearing, P.K.,Stewart, E.L.,Turnbull, P.S.,Weaver, S.L.,Williams, S.P.,Wisely, G.B.,Lambert, M.H. A New Series of Estrogen Receptor Modulators That Display Selectivity for Estrogen Receptor beta J.Med.Chem., 45:5492-5505, 2002 Cited by PubMed: 12459017 DOI: 10.1021/jm020291h PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation