1U3S

Crystal Structure of Estrogen Receptor beta complexed with WAY-797

Summary for 1U3S

Entry DOI	10.2210/pdb1u3s/pdb
Related	1U3Q 1U3R
Descriptor	Estrogen receptor beta, steroid receptor coactivator-1, 3-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-OL, ... (4 entities in total)
Functional Keywords	estrogen receptor, estrogen receptor beta, er-beta, er, estrogen, nuclear receptor, transcription factor, agonist, transcription
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: Q92731
Total number of polymer chains	4
Total formula weight	57546.02
Authors	Malamas, M.S.,Manas, E.S.,McDevitt, R.E.,Gunawan, I.,Xu, Z.B.,Collini, M.D.,Miller, C.P.,Dinh, T.,Henderson, R.A.,Keith Jr., J.C.,Harris, H.A. (deposition date: 2004-07-22, release date: 2005-07-26, Last modification date: 2024-02-14)
Primary citation	Malamas, M.S.,Manas, E.S.,McDevitt, R.E.,Gunawan, I.,Xu, Z.B.,Collini, M.D.,Miller, C.P.,Dinh, T.,Henderson, R.A.,Keith Jr., J.C.,Harris, H.A. Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands. J.Med.Chem., 47:5021-5040, 2004 Cited by PubMed: 15456246 DOI: 10.1021/jm049719y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation