2YJD

Stapled peptide bound to Estrogen Receptor Beta

Summary for 2YJD

Related2YLY 1L2J 2FSZ 1X7B 1X76 1NDE 2JJ3 1YY4 1U3S 1X78 1QKM 1U3R 1X7J 1U9E 1YYE 1U3Q 2YJA 2LDD 2LDA 2LDC
DescriptorESTROGEN RECEPTOR BETA, STAPLED PEPTIDE, 4-(2-PROPAN-2-YLOXYBENZIMIDAZOL-1-YL)PHENOL, ... (4 entities in total)
Functional Keywordshormone receptor-peptide complex, hormone receptor/peptide
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus  Q92731
Total number of polymer chains4
Total molecular weight57466.2
Authors
Phillips, C.,Roberts, L.R.,Schade, M.,Bent, A.,Davies, N.L.,Moore, R.,Pannifer, A.D.,Brown, D.G.,Pickford, A.R.,Irving, S.L. (deposition date: 2011-05-19, release date: 2011-08-03, Last modification date: 2017-01-25)
Primary citation
Phillips, C.,Roberts, L.R.,Schade, M.,Bazin, R.,Bent, A.,Davies, N.L.,Moore, R.,Pannifer, A.D.,Pickford, A.R.,Prior, S.H.,Read, C.M.,Scott, A.,Brown, D.G.,Xu, B.,Irving, S.L.
Design and Structure of Stapled Peptides Binding to Estrogen Receptors.
J.Am.Chem.Soc., 133:9696-, 2011
PubMed: 21612236 (PDB entries with the same primary citation)
DOI: 10.1021/JA202946K
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.93 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21751.8%9.0%11.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2yjd
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Molmil generated image of 2yjd
rotated about x axis by 90°
Molmil generated image of 2yjd
rotated about y axis by 90°