1X7J

CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH GENISTEIN

Summary for 1X7J

• Entry DOI: 10.2210/pdb1x7j/pdb
• Related: 1U3Q 1U3R 1U3S 1U9E 1X76 1X78 1X7B 1X7R
• Descriptor: Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1, GENISTEIN, ... (4 entities in total)
• Functional Keywords: estrogen receptor, estrogen receptor beta, er-beta, er, estrogen, nuclear receptor, transcription factor, agonist, transcription
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q92731
• Total number of polymer chains: 4
• Total formula weight: 57531.95

Authors

Manas, E.S.,Xu, Z.B.,Unwalla, R.J.,Somers, W.S. (deposition date: 2004-08-14, release date: 2005-03-01, Last modification date: 2024-04-03)

• Primary citation: Manas, E.S.,Xu, Z.B.,Unwalla, R.J.,Somers, W.S.; Understanding the Selectivity of Genistein for Human Estrogen Receptor-Beta Using X-Ray Crystallography and Computational Methods; Structure, 12:2197-2207, 2004; PubMed: 15576033; DOI: 10.1016/j.str.2004.09.015

Experimental method

X-RAY DIFFRACTION (2.3 Å)