2FSZ
A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor beta
Summary for 2FSZ
| Entry DOI | 10.2210/pdb2fsz/pdb |
| Descriptor | Estrogen receptor beta, 4-HYDROXYTAMOXIFEN (3 entities in total) |
| Functional Keywords | nuclear hormone binding domain, hormone-growth factor complex, hormone/growth factor |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus : Q92731 |
| Total number of polymer chains | 2 |
| Total formula weight | 57037.61 |
| Authors | Wang, Y. (deposition date: 2006-01-23, release date: 2006-07-11, Last modification date: 2024-02-14) |
| Primary citation | Wang, Y.,Chirgadze, N.Y.,Briggs, S.L.,Khan, S.,Jensen, E.V.,Burris, T.P. A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor beta Proc.Natl.Acad.Sci.Usa, 103:9908-9911, 2006 Cited by PubMed: 16782818DOI: 10.1073/pnas.0510596103 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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