2J0S
 
 | | The crystal structure of the Exon Junction Complex at 2.2 A resolution | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP *UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ... | | Authors: | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | | Deposit date: | 2006-08-04 | | Release date: | 2006-09-06 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | The Crystal Structure of the Exon Junction Complex Reveals How It Mantains a Stable Grip on Mrna
Cell(Cambridge,Mass.), 126, 2006
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2J0Q
 | | The crystal structure of the Exon Junction Complex at 3.2 A resolution | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ... | | Authors: | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | | Deposit date: | 2006-08-04 | | Release date: | 2006-08-30 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on Mrna.
Cell(Cambridge,Mass.), 126, 2006
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7ABH
 | | Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) | | Descriptor: | Cell division cycle 5-like protein, DNA/RNA-binding protein KIN17, MINX M3 pre-mRNA, ... | | Authors: | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | Deposit date: | 2020-09-07 | | Release date: | 2020-12-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
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2IY1
 | | SENP1 (mutant) full length SUMO1 | | Descriptor: | SENTRIN-SPECIFIC PROTEASE 1, SMALL UBIQUITIN-RELATED MODIFIER 1 | | Authors: | Shen, L, Dong, C, Naismith, J.H. | | Deposit date: | 2006-07-11 | | Release date: | 2006-08-15 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.46 Å) | | Cite: | Sumo Protease Senp1 Induces Isomerization of the Scissile Peptide Bond.
Nat.Struct.Mol.Biol., 13, 2006
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6ZV6
 | | Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage) | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Plassart, L, Shayan, R, Plisson-Chastang, C. | | Deposit date: | 2020-07-24 | | Release date: | 2021-05-12 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | The final step of 40S ribosomal subunit maturation is controlled by a dual key lock.
Elife, 10, 2021
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6ZUO
 | | Human RIO1(kd)-StHA late pre-40S particle, structural state A (pre 18S rRNA cleavage) | | Descriptor: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | | Authors: | Plassart, L, Shayan, R, Plisson-Chastang, C. | | Deposit date: | 2020-07-23 | | Release date: | 2021-05-12 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | The final step of 40S ribosomal subunit maturation is controlled by a dual key lock.
Elife, 10, 2021
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2DH9
 | | Solution structure of the C-terminal RNA binding domain in Heterogeneous nuclear ribonucleoprotein M | | Descriptor: | Heterogeneous nuclear ribonucleoprotein M | | Authors: | Ochi, T, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-03-23 | | Release date: | 2006-09-23 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the C-terminal RNA binding domain in Heterogeneous nuclear ribonucleoprotein M
To be Published
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2DGV
 | | Solution structure of the RNA binding domain in Heterogeneous nuclear ribonucleoprotein M | | Descriptor: | Heterogeneous nuclear ribonucleoprotein M | | Authors: | Abe, C, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-03-16 | | Release date: | 2006-09-16 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the RNA binding domain in Heterogeneous nuclear ribonucleoprotein M
To be Published
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7ASV
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7APK
 | | Structure of the human THO - UAP56 complex | | Descriptor: | Spliceosome RNA helicase DDX39B, THO complex subunit 1, THO complex subunit 2, ... | | Authors: | Hohmann, U, Puehringer, T, Plaschka, C. | | Deposit date: | 2020-10-17 | | Release date: | 2020-12-16 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of the human core transcription-export complex reveals a hub for multivalent interactions.
Elife, 9, 2020
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7ASU
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7AXZ
 | | Ku70/80 complex apo form | | Descriptor: | X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6 | | Authors: | Hnizda, A, Tesina, P, Novak, P, Blundell, T.L. | | Deposit date: | 2020-11-10 | | Release date: | 2021-02-10 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | SAP domain forms a flexible part of DNA aperture in Ku70/80.
Febs J., 288, 2021
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7A01
 | | The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism | | Descriptor: | 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES21, ... | | Authors: | Abaeva, I, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T.V, Hashem, Y, Hellen, C.U.T. | | Deposit date: | 2020-08-05 | | Release date: | 2020-12-30 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Cell Rep, 33, 2020
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7A5P
 | | Human C Complex Spliceosome - Medium-resolution PERIPHERY | | Descriptor: | Cell division cycle 5-like protein, Crooked neck-like protein 1, Eukaryotic initiation factor 4A-III, ... | | Authors: | Bertram, K, Kastner, B. | | Deposit date: | 2020-08-21 | | Release date: | 2020-10-14 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome.
Mol.Cell, 80, 2020
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2DZQ
 | | Solution Structure of RSGI RUH-066, a GTF2I domain in human cDNA | | Descriptor: | General transcription factor II-I repeat domain-containing protein 1 | | Authors: | Doi-Katayama, Y, Hirota, H, Tomizawa, T, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-09-30 | | Release date: | 2007-03-30 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of RSGI RUH-066, a GTF2I domain in human cDNA
To be published
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6ZVK
 | | The Halastavi arva virus (HalV) intergenic region IRES promotes translation by the simplest possible initiation mechanism | | Descriptor: | 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES17, ... | | Authors: | Abaeva, I.S, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T, Hashem, Y, Hellen, C.U.T. | | Deposit date: | 2020-07-24 | | Release date: | 2020-12-23 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Cell Rep, 33, 2020
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7ABF
 | | Human pre-Bact-1 spliceosome core structure | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | Deposit date: | 2020-09-07 | | Release date: | 2020-12-09 | | Last modified: | 2020-12-30 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
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2C9O
 | | 3D Structure of the human RuvB-like helicase RuvBL1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RUVB-LIKE 1 | | Authors: | Matias, P.M, Gorynia, S, Donner, P, Carrondo, M.A. | | Deposit date: | 2005-12-14 | | Release date: | 2006-10-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of the human AAA+ protein RuvBL1.
J. Biol. Chem., 281, 2006
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2IY0
 | | SENP1 (mutant) SUMO1 RanGAP | | Descriptor: | RAN GTPASE-ACTIVATING PROTEIN 1, SENTRIN-SPECIFIC PROTEASE 1, SMALL UBIQUITIN-RELATED MODIFIER 1 | | Authors: | Shen, L, Dong, C, Naismith, J.H. | | Deposit date: | 2006-07-11 | | Release date: | 2006-08-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Sumo Protease Senp1 Induces Isomerization of the Scissile Peptide Bond.
Nat.Struct.Mol.Biol., 13, 2006
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2DZR
 | | Solution Structure of RSGI RUH-067, a GTF2I domain in human cDNA | | Descriptor: | General transcription factor II-I repeat domain-containing protein 1 | | Authors: | Doi-Katayama, Y, Hirota, H, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-09-30 | | Release date: | 2007-03-30 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of RSGI RUH-067, a GTF2I domain in human cDNA
To be published
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2HYI
 | | Structure of the human exon junction complex with a trapped DEAD-box helicase bound to RNA | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*U)-3', MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Andersen, C.B.F, Le Hir, H, Andersen, G.R. | | Deposit date: | 2006-08-06 | | Release date: | 2006-08-15 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.
Science, 313, 2006
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2GRQ
 | | Crystal Structure of human RanGAP1-Ubc9-D127A | | Descriptor: | Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I | | Authors: | Yunus, A.A, Lima, C.D. | | Deposit date: | 2006-04-24 | | Release date: | 2006-05-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
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2GRP
 | | Crystal Structure of human RanGAP1-Ubc9-Y87A | | Descriptor: | Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I | | Authors: | Yunus, A.A, Lima, C.D. | | Deposit date: | 2006-04-24 | | Release date: | 2006-05-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
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2GRR
 | | Crystal Structure of human RanGAP1-Ubc9-D127S | | Descriptor: | Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I | | Authors: | Yunus, A.A, Lima, C.D. | | Deposit date: | 2006-04-24 | | Release date: | 2006-05-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
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5ZYA
 | | SF3b spliceosomal complex bound to E7107 | | Descriptor: | PHD finger-like domain-containing protein 5A, POTASSIUM ION, Splicing factor 3B subunit 1, ... | | Authors: | Finci, L.I, Larsen, N.A. | | Deposit date: | 2018-05-23 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.95 Å) | | Cite: | The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action
Genes Dev., 32, 2018
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