8HAG
Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (3.2 angstrom resolution)
Summary for 8HAG
Entry DOI | 10.2210/pdb8hag/pdb |
EMDB information | 34588 |
Descriptor | Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (6 entities in total) |
Functional Keywords | acetyl taransferase, complex, nucleosome, transferase, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 11 |
Total formula weight | 312677.15 |
Authors | Kikuchi, M.,Morita, S.,Wakamori, M.,Shin, S.,Uchikubo-Kamo, T.,Shirouzu, M.,Umehara, T. (deposition date: 2022-10-26, release date: 2023-05-17, Last modification date: 2023-07-26) |
Primary citation | Kikuchi, M.,Morita, S.,Wakamori, M.,Sato, S.,Uchikubo-Kamo, T.,Suzuki, T.,Dohmae, N.,Shirouzu, M.,Umehara, T. Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14:4103-4103, 2023 Cited by PubMed: 37460559DOI: 10.1038/s41467-023-39735-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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