8BOT

Cryo-EM structure of NHEJ supercomplex(trimer)

This is a non-PDB format compatible entry.

Summary for 8BOT

• Entry DOI: 10.2210/pdb8bot/pdb
• EMDB information: 16145
• Descriptor: DNA repair protein XRCC4, DNA (24-MER), DNA ligase 4, ... (10 entities in total)
• Functional Keywords: nhej, dna-pk, dna-pkcs, ku70, ku80, xlf, dna repair, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 25
• Total formula weight: 2411092.49

Authors

Hardwick, S.W.,Chaplin, A.K. (deposition date: 2022-11-15, release date: 2023-06-28, Last modification date: 2023-08-16)

• Primary citation: Hardwick, S.W.,Stavridi, A.K.,Chirgadze, D.Y.,De Oliveira, T.M.,Charbonnier, J.B.,Ropars, V.,Meek, K.,Blundell, T.L.,Chaplin, A.K.; Cryo-EM structure of a DNA-PK trimer: higher order oligomerisation in NHEJ.; Structure, 31:895-, 2023; PubMed: 37311458; DOI: 10.1016/j.str.2023.05.013

Experimental method

ELECTRON MICROSCOPY (7.76 Å)