7ABF

Human pre-Bact-1 spliceosome core structure

This is a non-PDB format compatible entry.

Summary for 7ABF

• Entry DOI: 10.2210/pdb7abf/pdb
• EMDB information: 11694
• Descriptor: Protein BUD31 homolog, WW domain-binding protein 11, SNW domain-containing protein 1, ... (18 entities in total)
• Functional Keywords: complex, spliceosome, catalytic activation, splicing
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 15
• Total formula weight: 1005868.79

Authors

Townsend, C.,Kastner, B.,Leelaram, M.N.,Bertram, K.,Stark, H.,Luehrmann, R. (deposition date: 2020-09-07, release date: 2020-12-09, Last modification date: 2020-12-30)

• Primary citation: Townsend, C.,Leelaram, M.N.,Agafonov, D.E.,Dybkov, O.,Will, C.L.,Bertram, K.,Urlaub, H.,Kastner, B.,Stark, H.,Luhrmann, R.; Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.; Science, 370:-, 2020; PubMed: 33243851; DOI: 10.1126/science.abc3753

Experimental method

ELECTRON MICROSCOPY (3.9 Å)