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7ABF

Human pre-Bact-1 spliceosome core structure

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(Q)
Protein BUD31 homologpolymer14417032.81UniProt (P41223)
Pfam (PF01125)
Homo sapiens (Human)Protein EDG-2,Protein G10 homolog
2B
(I)
Pre-mRNA-splicing factor 38Apolymer31237563.91UniProt (Q8NAV1)
Pfam (PF03371)
Pfam (PF12871)
Homo sapiens (Human)
3C
(A)
Pre-mRNA-processing-splicing factor 8polymer2335273974.31UniProt (Q6P2Q9)
Pfam (PF08082)
Pfam (PF08083)
Pfam (PF10598)
Pfam (PF10597)
Pfam (PF10596)
Pfam (PF12134)
Pfam (PF01398)
Pfam (PF08084)
Homo sapiens (Human)220 kDa U5 snRNP-specific protein,PRP8 homolog,Splicing factor Prp8,p220
4D
(r)
116 kDa U5 small nuclear ribonucleoprotein componentpolymer972109560.61UniProt (Q15029)
Pfam (PF16004)
Pfam (PF00009)
Pfam (PF03144)
Pfam (PF14492)
Pfam (PF03764)
Pfam (PF00679)
Homo sapiens (Human)Elongation factor Tu GTP-binding domain-containing protein 2,SNU114 homolog,hSNU114,U5 snRNP-specific protein,116 kDa,U5-116 kDa
5E
(N)
Zinc finger matrin-type protein 2polymer19923664.01UniProt (Q96NC0)
Pfam (PF12171)
Homo sapiens (Human)
6F
(q)
Ubiquitin-like protein 5polymer738560.91UniProt (Q9BZL1)
Pfam (PF00240)
Homo sapiens (Human)
7G
(R)
Spliceosome-associated protein CWC15 homologpolymer22926674.41UniProt (Q9P013)
Pfam (PF04889)
Homo sapiens (Human)
8H
(5)
U5 small nuclear RNApolymer11636908.71GenBank (36515)Homo sapiens (Human)
9I
(6)
U6 small nuclear RNApolymer10634098.31Homo sapiens (Human)
10J
(X)
WW domain-binding protein 11polymer64170098.61UniProt (Q9Y2W2)
Pfam (PF09429)
Homo sapiens (Human)WBP-11,Npw38-binding protein,NpwBP,SH3 domain-binding protein SNP70,Splicing factor that interacts with PQBP-1 and PP1
11K
(v)
SNW domain-containing protein 1polymer53661610.71UniProt (Q13573)
Pfam (PF02731)
Homo sapiens (Human)Nuclear protein SkiP,Nuclear receptor coactivator NCoA-62,Ski-interacting protein
12L
(G)
Pleiotropic regulator 1polymer51457280.81UniProt (O43660)
Pfam (PF00400)
Homo sapiens (Human)
13M
(Z)
MINX M3 RNApolymer23073712.41synthetic construct
14N
(K)
Microfibrillar-associated protein 1polymer43952050.51UniProt (P55081)
Pfam (PF06991)
Homo sapiens (Human)
15O
(A4)
Transcription elongation regulator 1polymer1077121870.31UniProt (O14776)
Pfam (PF00397)
Pfam (PF01846)
Homo sapiens (Human)TATA box-binding protein-associated factor 2S,Transcription factor CA150
16P
(A)
INOSITOL HEXAKISPHOSPHATEnon-polymer660.01Chemie (IHP)
17Q
(r)
GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
18R
(r)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains15
Total formula weight1004661.3
Non-Polymers*Number of molecules3
Total formula weight1207.5
All*Total formula weight1005868.8
*Water molecules are not included.

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PDB entries from 2024-10-30

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