6DCL

Crystal structure of UP1 bound to pri-miRNA-18a terminal loop

Summary for 6DCL

• Entry DOI: 10.2210/pdb6dcl/pdb
• Descriptor: Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3'), 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: rrm, hnrnp a1, rna, complex, rna binding protein, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 51095.57

Authors

Kooshapur, H.,Sattler, M. (deposition date: 2018-05-07, release date: 2018-06-27, Last modification date: 2024-03-13)

• Primary citation: Kooshapur, H.,Choudhury, N.R.,Simon, B.,Muhlbauer, M.,Jussupow, A.,Fernandez, N.,Jones, A.N.,Dallmann, A.,Gabel, F.,Camilloni, C.,Michlewski, G.,Caceres, J.F.,Sattler, M.; Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.; Nat Commun, 9:2479-2479, 2018; PubMed: 29946118; DOI: 10.1038/s41467-018-04871-9

Experimental method

X-RAY DIFFRACTION (2.497 Å)