6DCL
Crystal structure of UP1 bound to pri-miRNA-18a terminal loop
Summary for 6DCL
Entry DOI | 10.2210/pdb6dcl/pdb |
Descriptor | Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3'), 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | rrm, hnrnp a1, rna, complex, rna binding protein, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 51095.57 |
Authors | Kooshapur, H.,Sattler, M. (deposition date: 2018-05-07, release date: 2018-06-27, Last modification date: 2024-03-13) |
Primary citation | Kooshapur, H.,Choudhury, N.R.,Simon, B.,Muhlbauer, M.,Jussupow, A.,Fernandez, N.,Jones, A.N.,Dallmann, A.,Gabel, F.,Camilloni, C.,Michlewski, G.,Caceres, J.F.,Sattler, M. Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1. Nat Commun, 9:2479-2479, 2018 Cited by PubMed: 29946118DOI: 10.1038/s41467-018-04871-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.497 Å) |
Structure validation
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