7ZWA
CryoEM structure of Ku heterodimer bound to DNA and PAXX
Summary for 7ZWA
Entry DOI | 10.2210/pdb7zwa/pdb |
EMDB information | 14995 |
Descriptor | X-ray repair cross-complementing protein 6, X-ray repair cross-complementing protein 5, Protein PAXX, ... (6 entities in total) |
Functional Keywords | nhej, ku70, ku80, dna damage, dna binding protein, paxx |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 184022.16 |
Authors | Hardwick, S.W.,Kefala-Stavridi, A.,Chirgadze, D.Y.,Blundell, T.L.,Chaplin, A.K. (deposition date: 2022-05-19, release date: 2023-05-31, Last modification date: 2023-06-14) |
Primary citation | Seif-El-Dahan, M.,Kefala-Stavridi, A.,Frit, P.,Hardwick, S.W.,Chirgadze, D.Y.,Maia De Oliviera, T.,Britton, S.,Barboule, N.,Bossaert, M.,Pandurangan, A.P.,Meek, K.,Blundell, T.L.,Ropars, V.,Calsou, P.,Charbonnier, J.B.,Chaplin, A.K. PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9:eadg2834-eadg2834, 2023 Cited by PubMed: 37256950DOI: 10.1126/sciadv.adg2834 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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