7ZJ2
Amyloid fibril (in vitro) from full-length hnRNPA1 protein
Summary for 7ZJ2
Entry DOI | 10.2210/pdb7zj2/pdb |
EMDB information | 14739 |
Descriptor | Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (1 entity in total) |
Functional Keywords | amyloidosis, misfolding disease, inflammation, prion, protein fibril, nuclear protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 12 |
Total formula weight | 410954.72 |
Authors | Sharma, K.,Banerjee, S.,Schmidt, M.,Faendrich, M. (deposition date: 2022-04-08, release date: 2023-08-02, Last modification date: 2024-07-24) |
Primary citation | Sharma, K.,Banerjee, S.,Savran, D.,Rajes, C.,Wiese, S.,Girdhar, A.,Schwierz, N.,Lee, C.,Shorter, J.,Schmidt, M.,Guo, L.,Fandrich, M. Cryo-EM Structure of the Full-length hnRNPA1 Amyloid Fibril. J.Mol.Biol., 435:168211-168211, 2023 Cited by PubMed: 37481159DOI: 10.1016/j.jmb.2023.168211 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.32 Å) |
Structure validation
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