7ZJ2

Amyloid fibril (in vitro) from full-length hnRNPA1 protein

Summary for 7ZJ2

Entry DOI	10.2210/pdb7zj2/pdb
EMDB information	14739
Descriptor	Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (1 entity in total)
Functional Keywords	amyloidosis, misfolding disease, inflammation, prion, protein fibril, nuclear protein
Biological source	Homo sapiens (human)
Total number of polymer chains	12
Total formula weight	410954.72
Authors	Sharma, K.,Banerjee, S.,Schmidt, M.,Faendrich, M. (deposition date: 2022-04-08, release date: 2023-08-02, Last modification date: 2023-08-09)
Primary citation	Sharma, K.,Banerjee, S.,Savran, D.,Rajes, C.,Wiese, S.,Girdhar, A.,Schwierz, N.,Lee, C.,Shorter, J.,Schmidt, M.,Guo, L.,Fandrich, M. Cryo-EM Structure of the Full-length hnRNPA1 Amyloid Fibril. J.Mol.Biol., 435:168211-168211, 2023 Cited by PubMed: 37481159 DOI: 10.1016/j.jmb.2023.168211 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.32 Å)

Structure validation