7ZJ2
Amyloid fibril (in vitro) from full-length hnRNPA1 protein
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003723 | molecular_function | RNA binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003723 | molecular_function | RNA binding |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0003723 | molecular_function | RNA binding |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003723 | molecular_function | RNA binding |
| E | 0003676 | molecular_function | nucleic acid binding |
| E | 0003723 | molecular_function | RNA binding |
| F | 0003676 | molecular_function | nucleic acid binding |
| F | 0003723 | molecular_function | RNA binding |
| G | 0003676 | molecular_function | nucleic acid binding |
| G | 0003723 | molecular_function | RNA binding |
| H | 0003676 | molecular_function | nucleic acid binding |
| H | 0003723 | molecular_function | RNA binding |
| I | 0003676 | molecular_function | nucleic acid binding |
| I | 0003723 | molecular_function | RNA binding |
| J | 0003676 | molecular_function | nucleic acid binding |
| J | 0003723 | molecular_function | RNA binding |
| K | 0003676 | molecular_function | nucleic acid binding |
| K | 0003723 | molecular_function | RNA binding |
| L | 0003676 | molecular_function | nucleic acid binding |
| L | 0003723 | molecular_function | RNA binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| A | MET1 | |
| B | MET1 | |
| C | MET1 | |
| D | MET1 | |
| E | MET1 | |
| F | MET1 | |
| G | MET1 | |
| H | MET1 | |
| I | MET1 | |
| J | MET1 | |
| K | MET1 | |
| L | MET1 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER2 | |
| B | SER2 | |
| C | SER2 | |
| D | SER2 | |
| E | SER2 | |
| F | SER2 | |
| G | SER2 | |
| H | SER2 | |
| I | SER2 | |
| J | SER2 | |
| K | SER2 | |
| L | SER2 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS3 | |
| B | LYS3 | |
| C | LYS3 | |
| D | LYS3 | |
| E | LYS3 | |
| F | LYS3 | |
| G | LYS3 | |
| H | LYS3 | |
| I | LYS3 | |
| J | LYS3 | |
| K | LYS3 | |
| L | LYS3 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER4 | |
| B | SER4 | |
| C | SER4 | |
| D | SER4 | |
| E | SER4 | |
| F | SER4 | |
| G | SER4 | |
| H | SER4 | |
| I | SER4 | |
| J | SER4 | |
| K | SER4 | |
| L | SER4 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER6 | |
| B | SER6 | |
| C | SER6 | |
| D | SER6 | |
| E | SER6 | |
| F | SER6 | |
| G | SER6 | |
| H | SER6 | |
| I | SER6 | |
| J | SER6 | |
| K | SER6 | |
| L | SER6 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P49312 |
| Chain | Residue | Details |
| A | SER22 | |
| B | SER22 | |
| C | SER22 | |
| D | SER22 | |
| E | SER22 | |
| F | SER22 | |
| G | SER22 | |
| H | SER22 | |
| I | SER22 | |
| J | SER22 | |
| K | SER22 | |
| L | SER22 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 12 |
| Details | MOD_RES: Phosphoserine; by MKNK2 => ECO:0000269|PubMed:16111636 |
| Chain | Residue | Details |
| A | SER192 | |
| B | SER192 | |
| C | SER192 | |
| D | SER192 | |
| E | SER192 | |
| F | SER192 | |
| G | SER192 | |
| H | SER192 | |
| I | SER192 | |
| J | SER192 | |
| K | SER192 | |
| L | SER192 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 12 |
| Details | MOD_RES: Omega-N-methylarginine; alternate => ECO:0000250|UniProtKB:P49312 |
| Chain | Residue | Details |
| A | ARG194 | |
| B | ARG194 | |
| C | ARG194 | |
| D | ARG194 | |
| E | ARG194 | |
| F | ARG194 | |
| G | ARG194 | |
| H | ARG194 | |
| I | ARG194 | |
| J | ARG194 | |
| K | ARG194 | |
| L | ARG194 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 12 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692 |
| Chain | Residue | Details |
| A | SER199 | |
| B | SER199 | |
| C | SER199 | |
| D | SER199 | |
| E | SER199 | |
| F | SER199 | |
| G | SER199 | |
| H | SER199 | |
| I | SER199 | |
| J | SER199 | |
| K | SER199 | |
| L | SER199 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 24 |
| Details | MOD_RES: Omega-N-methylarginine; alternate => ECO:0000269|Ref.9, ECO:0007744|PubMed:24129315 |
| Chain | Residue | Details |
| A | ARG206 | |
| A | ARG225 | |
| B | ARG206 | |
| B | ARG225 | |
| C | ARG206 | |
| C | ARG225 | |
| D | ARG206 | |
| D | ARG225 | |
| E | ARG206 | |
| E | ARG225 | |
| F | ARG206 | |
| F | ARG225 | |
| G | ARG206 | |
| G | ARG225 | |
| H | ARG206 | |
| H | ARG225 | |
| I | ARG206 | |
| I | ARG225 | |
| J | ARG206 | |
| J | ARG225 | |
| K | ARG206 | |
| K | ARG225 | |
| L | ARG206 | |
| L | ARG225 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 24 |
| Details | MOD_RES: Omega-N-methylarginine; alternate => ECO:0007744|PubMed:24129315 |
| Chain | Residue | Details |
| A | ARG218 | |
| A | ARG232 | |
| B | ARG218 | |
| B | ARG232 | |
| C | ARG218 | |
| C | ARG232 | |
| D | ARG218 | |
| D | ARG232 | |
| E | ARG218 | |
| E | ARG232 | |
| F | ARG218 | |
| F | ARG232 | |
| G | ARG218 | |
| G | ARG232 | |
| H | ARG218 | |
| H | ARG232 | |
| I | ARG218 | |
| I | ARG232 | |
| J | ARG218 | |
| J | ARG232 | |
| K | ARG218 | |
| K | ARG232 | |
| L | ARG218 | |
| L | ARG232 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 12 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS3 | |
| B | LYS3 | |
| C | LYS3 | |
| D | LYS3 | |
| E | LYS3 | |
| F | LYS3 | |
| G | LYS3 | |
| H | LYS3 | |
| I | LYS3 | |
| J | LYS3 | |
| K | LYS3 | |
| L | LYS3 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 48 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS78 | |
| A | LYS179 | |
| A | LYS183 | |
| B | LYS78 | |
| B | LYS179 | |
| B | LYS183 | |
| C | LYS78 | |
| C | LYS179 | |
| C | LYS183 | |
| D | LYS78 | |
| D | LYS179 | |
| D | LYS183 | |
| E | LYS78 | |
| E | LYS179 | |
| E | LYS183 | |
| F | LYS78 | |
| F | LYS179 | |
| F | LYS183 | |
| G | LYS78 | |
| G | LYS179 | |
| G | LYS183 | |
| H | LYS78 | |
| H | LYS179 | |
| H | LYS183 | |
| I | LYS78 | |
| I | LYS179 | |
| I | LYS183 | |
| J | LYS78 | |
| J | LYS179 | |
| J | LYS183 | |
| K | LYS78 | |
| K | LYS179 | |
| K | LYS183 | |
| L | LYS78 | |
| L | LYS179 | |
| L | LYS183 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 12 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS8 | |
| B | LYS8 | |
| C | LYS8 | |
| D | LYS8 | |
| E | LYS8 | |
| F | LYS8 | |
| G | LYS8 | |
| H | LYS8 | |
| I | LYS8 | |
| J | LYS8 | |
| K | LYS8 | |
| L | LYS8 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 12 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:15161980 |
| Chain | Residue | Details |
| A | LYS113 | |
| B | LYS113 | |
| C | LYS113 | |
| D | LYS113 | |
| E | LYS113 | |
| F | LYS113 | |
| G | LYS113 | |
| H | LYS113 | |
| I | LYS113 | |
| J | LYS113 | |
| K | LYS113 | |
| L | LYS113 |
