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PDB: 43 件
3GGP
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Crystal structure of prephenate dehydrogenase from A. aeolicus in complex with hydroxyphenyl propionate and NAD+
分子名称: CHLORIDE ION, HYDROXYPHENYL PROPIONIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Sun, W, Shahinas, D, Kimber, M.S, Christendat, D.
登録日2009-03-01
公開日2009-03-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The Crystal Structure of Aquifex aeolicus Prephenate Dehydrogenase Reveals the Mode of Tyrosine Inhibition.
J.Biol.Chem., 284, 2009
3GGO
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Crystal structure of prephenate dehydrogenase from A. aeolicus with HPP and NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, Prephenate dehydrogenase
著者Sun, W, Shahinas, D, Christendat, D.
登録日2009-03-01
公開日2009-03-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Crystal Structure of Aquifex aeolicus Prephenate Dehydrogenase Reveals the Mode of Tyrosine Inhibition.
J.Biol.Chem., 284, 2009
3GGG
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The crystal structure of A. aeolicus prephenate dehydrogenase in complex with tyrosine and NAD+
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Prephenate dehydrogenase, TYROSINE
著者Sun, W, Shahinas, D, Christendat, D.
登録日2009-02-27
公開日2009-03-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献The Crystal Structure of Aquifex aeolicus Prephenate Dehydrogenase Reveals the Mode of Tyrosine Inhibition.
J.Biol.Chem., 284, 2009
7YBF
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BU of 7ybf by Molmil
Crystal structure of inner membrane protein Sad1 in complex with histone H2A-H2B
分子名称: Histone H2B-alpha,Histone H2A-beta, Spindle pole body-associated protein sad1
著者Sun, W, Hu, C, Chen, Y.
登録日2022-06-29
公開日2024-01-03
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The SUN-family protein Sad1 mediates heterochromatin spatial organization through interaction with histone H2A-H2B.
Nat Commun, 15, 2024
4KK1
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Crystal Structure of TSC1 core domain from S. pombe
分子名称: Tuberous sclerosis 1 protein homolog
著者Sun, W, Zhu, Y, Wang, Z.Z, Zhong, Q, Gao, F, Lou, J.Z, Gong, W.M, Xu, W.Q.
登録日2013-05-05
公開日2013-07-17
最終更新日2013-07-31
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of the yeast TSC1 core domain and implications for tuberous sclerosis pathological mutations.
Nat Commun, 4, 2013
4KK0
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BU of 4kk0 by Molmil
Crystal Structure of TSC1 core domain from S. pombe
分子名称: Tuberous sclerosis 1 protein homolog
著者Sun, W, Zhu, Y, Wang, Z.Z, Zhong, Q, Gao, F, Lou, J.Z, Gong, W.M, Xu, W.Q.
登録日2013-05-05
公開日2013-07-17
最終更新日2013-07-31
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the yeast TSC1 core domain and implications for tuberous sclerosis pathological mutations.
Nat Commun, 4, 2013
5YDE
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BU of 5yde by Molmil
Crystal structure of a disease-related gene, hCDC73(1-111)
分子名称: Parafibromin
著者Sun, W, Kuang, X.L, Liu, Y.P, Tian, L.F, Yan, X.X, Xu, W.Q.
登録日2017-09-13
公開日2017-12-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.023 Å)
主引用文献Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome
Sci Rep, 7, 2017
5YDF
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Crystal structure of a disease-related gene, hCDC73(1-100)
分子名称: Parafibromin
著者Sun, W, Kuang, X.L, Liu, Y.P, Tian, L.F, Yan, X.X, Xu, W.Q.
登録日2017-09-13
公開日2017-12-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.399 Å)
主引用文献Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome
Sci Rep, 7, 2017
2AS0
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Crystal Structure of PH1915 (APC 5817): A Hypothetical RNA Methyltransferase
分子名称: hypothetical protein PH1915
著者Sun, W, Xu, X, Pavlova, M, Edwards, A.M, Joachimiak, A, Savchenko, A, Christendat, D, Midwest Center for Structural Genomics (MCSG)
登録日2005-08-22
公開日2005-09-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of a novel SAM-dependent methyltransferase PH1915 from Pyrococcus horikoshii.
Protein Sci., 14, 2005
2G5C
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Crystal Structure of Prephenate Dehydrogenase from Aquifex aeolicus
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, prephenate dehydrogenase
著者Sun, W, Singh, S, Zhang, R, Turnbull, J.L, Christendat, D.
登録日2006-02-22
公開日2006-03-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Prephenate Dehydrogenase from Aquifex aeolicus: Insights into the Catalytic Mechanism
J.Biol.Chem., 281, 2006
6JE9
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Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers
分子名称: AcrIIC3, CRISPR-associated endonuclease Cas9, sgRNA
著者Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
登録日2019-02-04
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6JE4
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Crystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomers
分子名称: 1,2-ETHANEDIOL, AcrIIC3, CRISPR-associated endonuclease Cas9, ...
著者Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
登録日2019-02-04
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.069 Å)
主引用文献Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6JE3
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Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM) with 5 nt overhang
分子名称: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, non-target DNA strand, ...
著者Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
登録日2019-02-03
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.931 Å)
主引用文献Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6JFU
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BU of 6jfu by Molmil
Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM)
分子名称: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, non-target strand, ...
著者Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
登録日2019-02-12
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6KC7
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BU of 6kc7 by Molmil
Crystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in seed-base paring state
分子名称: CRISPR-associated endonuclease Cas9, DNA (5'-D(*AP*TP*AP*TP*GP*AP*TP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*TP*CP*AP*TP*AP*TP*GP*TP*AP*AP*AP*GP*TP*T)-3'), ...
著者Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
登録日2019-06-27
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6JDV
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BU of 6jdv by Molmil
Crystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in catalytic state
分子名称: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, MAGNESIUM ION, ...
著者Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
登録日2019-02-02
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6JDQ
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BU of 6jdq by Molmil
Crystal structure of Nme1Cas9 in complex with sgRNA
分子名称: CRISPR-associated endonuclease Cas9, sgRNA
著者Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
登録日2019-02-02
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6KC8
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BU of 6kc8 by Molmil
Crystal structure of WT Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in post-cleavage state
分子名称: CRISPR-associated endonuclease Cas9, DNA (5'-D(*AP*TP*AP*TP*GP*AP*TP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*TP*CP*AP*TP*AP*TP*GP*TP*A)-3'), ...
著者Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
登録日2019-06-27
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
8HNW
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BU of 8hnw by Molmil
Crystal structure of HpaCas9-sgRNA surveillance complex bound to double-stranded DNA
分子名称: CRISPR-associated endonuclease Cas9, Non-target strand, Target strand, ...
著者Sun, W, Cheng, Z, Wang, Y.
登録日2022-12-08
公開日2023-07-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
8HNS
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BU of 8hns by Molmil
Crystal structure of an anti-CRISPR protein AcrIIC4 in apo form
分子名称: GLYCEROL, anti-CRISPR protein AcrIIC4
著者Sun, W, Cheng, Z, Yang, J, Wang, Y.
登録日2022-12-08
公開日2023-07-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
8HNT
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BU of 8hnt by Molmil
Crystal structure of anti-CRISPR protein AcrIIC4 bound to HpaCas9-sgRNA surveillance complex
分子名称: CRISPR-associated endonuclease Cas9, anti-CRISPR protein AcrIIC4, sgRNA
著者Sun, W, Cheng, Z, Wang, Y.
登録日2022-12-08
公開日2023-07-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
8HNV
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CryoEM structure of HpaCas9-sgRNA-dsDNA in the presence of AcrIIC4
分子名称: CRISPR-associated endonuclease Cas9, anti-CRISPR protein AcrIIC4, non-target strand, ...
著者Sun, W, Cheng, Z, Wang, J, Yang, X, Wang, Y.
登録日2022-12-08
公開日2023-07-19
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
7D68
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BU of 7d68 by Molmil
Cryo-EM structure of the human glucagon-like peptide-2 receptor-Gs protein complex
分子名称: Glucagon-like peptide 2 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Sun, W, Chen, L, Zhou, Q, Zhao, L, Zhang, H, Cong, Z, Shen, D, Zhao, F, Zhou, F, Cai, X, Chen, Y, Zhou, Y, Gadgaard, S, van der Velden, W.J, Zhao, S, Jiang, Y, Rosenkilde, M.M, Yang, D, Xu, H.E, Zhang, Y, Wang, M.
登録日2020-09-29
公開日2020-12-16
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor.
Cell Res., 30, 2020
3ZIF
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BU of 3zif by Molmil
Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly
分子名称: HEXON PROTEIN, PENTON PROTEIN, PIX, ...
著者Cheng, L, Huang, X, Li, X, Xiong, W, Sun, W, Yang, C, Zhang, K, Wang, Y, Liu, H, Ji, G, Sun, F, Zheng, C, Zhu, P.
登録日2013-01-09
公開日2014-01-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-Em Structures of Two Bovine Adenovirus Type 3 Intermediates
Virology, 450, 2014
6LTU
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BU of 6ltu by Molmil
Crystal structure of Cas12i2 ternary complex with double Mg2+ bound in catalytic pocket
分子名称: 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ...
著者Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y.
登録日2020-01-23
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Nat Commun, 11, 2020

 

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