8HNS

Crystal structure of an anti-CRISPR protein AcrIIC4 in apo form

Summary for 8HNS

Entry DOI	10.2210/pdb8hns/pdb
Descriptor	anti-CRISPR protein AcrIIC4, GLYCEROL (3 entities in total)
Functional Keywords	anti-crispr protein, cleavage inhibition, dimer, antimicrobial protein
Biological source	Haemophilus parainfluenzae
Total number of polymer chains	2
Total formula weight	20328.98
Authors	Sun, W.,Cheng, Z.,Yang, J.,Wang, Y. (deposition date: 2022-12-08, release date: 2023-07-19, Last modification date: 2023-08-02)
Primary citation	Sun, W.,Cheng, Z.,Wang, J.,Yang, J.,Li, X.,Wang, J.,Chen, M.,Yang, X.,Sheng, G.,Lou, J.,Wang, Y. AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation. Proc.Natl.Acad.Sci.USA, 120:e2303675120-e2303675120, 2023 Cited by PubMed: 37494395 DOI: 10.1073/pnas.2303675120 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.54 Å)

Structure validation