6JDQ

Crystal structure of Nme1Cas9 in complex with sgRNA

Summary for 6JDQ

Entry DOI	10.2210/pdb6jdq/pdb
Descriptor	CRISPR-associated endonuclease Cas9, sgRNA (3 entities in total)
Functional Keywords	crispr-cas9, nmecas9, binary, nme1cas9, hydrolase, hydrolase-rna complex, hydrolase/rna
Biological source	Neisseria meningitidis serogroup C (strain 8013) More
Total number of polymer chains	2
Total formula weight	168994.55
Authors	Sun, W.,Yang, J.,Cheng, Z.,Liu, C.,Wang, K.,Huang, X.,Wang, Y. (deposition date: 2019-02-02, release date: 2019-11-06, Last modification date: 2023-11-22)
Primary citation	Sun, W.,Yang, J.,Cheng, Z.,Amrani, N.,Liu, C.,Wang, K.,Ibraheim, R.,Edraki, A.,Huang, X.,Wang, M.,Wang, J.,Liu, L.,Sheng, G.,Yang, Y.,Lou, J.,Sontheimer, E.J.,Wang, Y. Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. Mol.Cell, 76:938-, 2019 Cited by PubMed: 31668930 DOI: 10.1016/j.molcel.2019.09.025 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation