4KK0
Crystal Structure of TSC1 core domain from S. pombe
Summary for 4KK0
Entry DOI | 10.2210/pdb4kk0/pdb |
Related | 4KK1 |
Descriptor | Tuberous sclerosis 1 protein homolog (1 entity in total) |
Functional Keywords | heat repeat, tumor suppressor, immune system |
Biological source | Schizosaccharomyces pombe (Fission yeast) |
Cellular location | Cytoplasm: Q09778 |
Total number of polymer chains | 10 |
Total formula weight | 537405.82 |
Authors | Sun, W.,Zhu, Y.,Wang, Z.Z.,Zhong, Q.,Gao, F.,Lou, J.Z.,Gong, W.M.,Xu, W.Q. (deposition date: 2013-05-05, release date: 2013-07-17, Last modification date: 2013-07-31) |
Primary citation | Sun, W.,Zhu, Y.J.,Wang, Z.,Zhong, Q.,Gao, F.,Lou, J.,Gong, W.,Xu, W. Crystal structure of the yeast TSC1 core domain and implications for tuberous sclerosis pathological mutations. Nat Commun, 4:2135-2135, 2013 Cited by PubMed: 23857276DOI: 10.1038/ncomms3135 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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