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3U50
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BU of 3u50 by Molmil
Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 OB-C
Descriptor: Telomerase-associated protein 82, ZINC ION
Authors:Zeng, Z, Huang, J, Yang, Y, Lei, M.
Deposit date:2011-10-10
Release date:2011-12-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U58
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BU of 3u58 by Molmil
Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 AB
Descriptor: DNA (5'-D(*GP*GP*GP*T)-3'), Tetrahymena Teb1 AB
Authors:Zeng, Z, Huang, J, Yang, Y, Lei, M.
Deposit date:2011-10-11
Release date:2011-12-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.613 Å)
Cite:Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
4WF1
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BU of 4wf1 by Molmil
Crystal structure of the E. coli ribosome bound to negamycin.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Olivier, N.B, Altman, R.B, Noeske, J, Basarab, G.S, Code, E, Ferguson, A.D, Gao, N, Huang, J, Juette, M.F, Livchak, S, Miller, M.D, Prince, D.B, Cate, J.H.D, Buurman, E.T, Blanchard, S.C.
Deposit date:2014-09-11
Release date:2014-11-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.
Proc.Natl.Acad.Sci.USA, 111, 2014
6LK0
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BU of 6lk0 by Molmil
Crystal structure of human wild type TRIP13
Descriptor: Pachytene checkpoint protein 2 homolog
Authors:Wang, Y, Huang, J, Li, B, Xue, H, Tricot, G, Hu, L, Xu, Z, Sun, X, Chang, S, Gao, L, Tao, Y, Xu, H, Xie, Y, Xiao, W, Yu, D, Kong, Y, Chen, G, Sun, X, Lian, F, Zhang, N, Wu, X, Mao, Z, Zhan, F, Zhu, W, Shi, J.
Deposit date:2019-12-17
Release date:2020-01-22
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Cancer Res., 80, 2020
4GOY
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BU of 4goy by Molmil
The crystal structure of human fascin 1 K41A mutant
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BROMIDE ION, CHLORIDE ION, ...
Authors:Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y.
Deposit date:2012-08-20
Release date:2012-11-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular mechanism of fascin function in filopodial formation.
J.Biol.Chem., 288, 2013
4GP0
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BU of 4gp0 by Molmil
The crystal structure of human fascin 1 R149A K150A R151A mutant
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BROMIDE ION, ...
Authors:Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y.
Deposit date:2012-08-20
Release date:2012-11-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mechanism of fascin function in filopodial formation.
J.Biol.Chem., 288, 2013
4GP3
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BU of 4gp3 by Molmil
The crystal structure of human fascin 1 K358A mutant
Descriptor: BROMIDE ION, CHLORIDE ION, Fascin, ...
Authors:Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y.
Deposit date:2012-08-20
Release date:2012-11-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Molecular mechanism of fascin function in filopodial formation.
J.Biol.Chem., 288, 2013
4GOV
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BU of 4gov by Molmil
The crystal structure of human fascin 1 S39D mutant
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BROMIDE ION, CHLORIDE ION, ...
Authors:Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y.
Deposit date:2012-08-20
Release date:2012-11-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular mechanism of fascin function in filopodial formation.
J.Biol.Chem., 288, 2013
8S9C
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BU of 8s9c by Molmil
Cryo-EM structure of Nav1.7 with CBZ
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Fan, X, Huang, J, Yan, N.
Deposit date:2023-03-27
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural mapping of Na v 1.7 antagonists.
Nat Commun, 14, 2023
8S9B
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BU of 8s9b by Molmil
Cryo-EM structure of Nav1.7 with LCM
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Fan, X, Huang, J, Yan, N.
Deposit date:2023-03-27
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural mapping of Na v 1.7 antagonists.
Nat Commun, 14, 2023
4U27
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BU of 4u27 by Molmil
Crystal structure of the E. coli ribosome bound to flopristin and linopristin.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D.
Deposit date:2014-07-16
Release date:2014-07-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
4U20
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BU of 4u20 by Molmil
Crystal structure of the E. coli ribosome bound to flopristin.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D.
Deposit date:2014-07-16
Release date:2014-07-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
4U1U
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BU of 4u1u by Molmil
Crystal structure of the E. coli ribosome bound to quinupristin.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D.
Deposit date:2014-07-16
Release date:2014-07-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
4U24
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BU of 4u24 by Molmil
Crystal structure of the E. coli ribosome bound to dalfopristin.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D.
Deposit date:2014-07-16
Release date:2014-07-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
4U26
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BU of 4u26 by Molmil
Crystal structure of the E. coli ribosome bound to dalfopristin and quinupristin.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D.
Deposit date:2014-07-16
Release date:2014-07-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
4U25
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BU of 4u25 by Molmil
Crystal structure of the E. coli ribosome bound to virginiamycin M1.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D.
Deposit date:2014-07-16
Release date:2014-07-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
4U1V
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BU of 4u1v by Molmil
Crystal structure of the E. coli ribosome bound to linopristin.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D.
Deposit date:2014-07-16
Release date:2014-07-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
4RSY
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BU of 4rsy by Molmil
Crystal structures of the Human leukotriene A4 Hydrolase complex with a potential inhibitor H7
Descriptor: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, ACETIC ACID, IMIDAZOLE, ...
Authors:Ouyang, P, Lu, W, Cui, K, Huang, J.
Deposit date:2014-11-12
Release date:2015-12-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structure of Human Leukotriene A4 Hydrolase in complex with inhibitor H1
To be Published
4RVB
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BU of 4rvb by Molmil
Crystal Structure Analysis of the Human Leukotriene A4 Hydrolase
Descriptor: ACETATE ION, ACETIC ACID, GLYCEROL, ...
Authors:Ouyang, P, Lu, W, Cui, K, Huang, J.
Deposit date:2014-11-25
Release date:2015-12-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal Structure Analysis of the Human Leukotriene A4 Hydrolase
To be Published
2XCT
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BU of 2xct by Molmil
The twinned 3.35A structure of S. aureus Gyrase complex with Ciprofloxacin and DNA
Descriptor: 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, 5'-D(AP*GP*CP*CP*GP*TP*AP*G)-3', 5'-D(GP*TP*AP*CP*AP*CP*CP*GP*CP*AP*CP*A)-3', ...
Authors:Bax, B.D, Chan, P, Eggleston, D.S, Fosberry, A, Gentry, D.R, Gorrec, F, Giordano, I, Hann, M.M, Hennessy, A, Hibbs, M, Huang, J, Jones, E, Jones, J, Brown, K.K, Lewis, C.J, May, E, Singh, O, Spitzfaden, C, Shen, C, Shillings, A, Theobald, A, Wohlkonig, A, Pearson, N.D, Gwynn, M.N.
Deposit date:2010-04-25
Release date:2010-08-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Type Iia Topoisomerase Inhibition by a New Class of Antibacterial Agents.
Nature, 466, 2010
2XCQ
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BU of 2xcq by Molmil
The 2.98A crystal structure of the catalytic core (B'A' region) of Staphylococcus aureus DNA Gyrase
Descriptor: DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A
Authors:Bax, B.D, Chan, P.F, Eggleston, D.S, Fosberry, A, Gentry, D.R, Gorrec, F, Giordano, I, Hann, M.M, Hennessy, A, Hibbs, M, Huang, J, Jones, E, Jones, J, Brown, K.K, Lewis, C.J, May, E.W, Singh, O, Spitzfaden, C, Shen, C, Shillings, A, Theobald, A.F, Wohlkonig, A, Pearson, N.D, Gwynn, M.N.
Deposit date:2010-04-24
Release date:2010-08-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Type Iia Topoisomerase Inhibition by a New Class of Antibacterial Agents.
Nature, 466, 2010
2XCS
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BU of 2xcs by Molmil
The 2.1A crystal structure of S. aureus Gyrase complex with GSK299423 and DNA
Descriptor: 5'-5UA*D(GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP *CP*TP*AP*CP*GP*GP*CP*T)-3', 6-METHOXY-4-(2-{4-[([1,3]OXATHIOLO[5,4-C]PYRIDIN-6-YLMETHYL)AMINO]PIPERIDIN-1-YL}ETHYL)QUINOLINE-3-CARBONITRILE, DNA GYRASE SUBUNIT B, ...
Authors:Bax, B.D, Chan, P.F, Eggleston, D.S, Fosberry, A, Gentry, D.R, Gorrec, F, Giordano, I, Hann, M.M, Hennessy, A, Hibbs, M, Huang, J, Jones, E, Jones, J, Brown, K.K, Lewis, C.J, May, E.W, Singh, O, Spitzfaden, C, Shen, C, Shillings, A, Theobald, A.F, Wohlkonig, A, Pearson, N.D, Gwynn, M.N.
Deposit date:2010-04-25
Release date:2010-08-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Type Iia Topoisomerase Inhibition by a New Class of Antibacterial Agents.
Nature, 466, 2010
2XCR
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BU of 2xcr by Molmil
The 3.5A crystal structure of the catalytic core (B'A' region) of Staphylococcus aureus DNA Gyrase complexed with GSK299423 and DNA
Descriptor: 5'-D(*5UA*GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP*CP*TP*AP*CP*GP *GP*CP*TP)-3', 5'-D(*AP*GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP*CP*TP*AP*CP*GP *GP*CP*TP)-3', 6-METHOXY-4-(2-{4-[([1,3]OXATHIOLO[5,4-C]PYRIDIN-6-YLMETHYL)AMINO]PIPERIDIN-1-YL}ETHYL)QUINOLINE-3-CARBONITRILE, ...
Authors:Bax, B.D, Chan, P.F, Eggleston, D.S, Fosberry, A, Gentry, D.R, Gorrec, F, Giordano, I, Hann, M.M, Hennessy, A, Hibbs, M, Huang, J, Jones, E, Jones, J, Brown, K.K, Lewis, C.J, May, E.W, Singh, O, Spitzfaden, C, Shen, C, Shillings, A, Theobald, A.F, Wohlkonig, A, Pearson, N.D, Gwynn, M.N.
Deposit date:2010-04-25
Release date:2010-08-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Type Iia Topoisomerase Inhibition by a New Class of Antibacterial Agents.
Nature, 466, 2010
2XCO
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BU of 2xco by Molmil
The 3.1A crystal structure of the catalytic core (B'A' region) of Staphylococcus aureus DNA Gyrase
Descriptor: CALCIUM ION, DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A
Authors:Bax, B.D, Chan, P.F, Eggleston, D.S, Fosberry, A, Gentry, D.R, Gorrec, F, Giordano, I, Hann, M.M, Hennessy, A, Hibbs, M, Huang, J, Jones, E, Jones, J, Brown, K.K, Lewis, C.J, May, E.W, Singh, O, Spitzfaden, C, Shen, C, Shillings, A, Theobald, A.F, Wohlkonig, A, Pearson, N.D, Gwynn, M.N.
Deposit date:2010-04-24
Release date:2010-08-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Type Iia Topoisomerase Inhibition by a New Class of Antibacterial Agents.
Nature, 466, 2010
7S0F
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BU of 7s0f by Molmil
Isoproterenol bound beta1 adrenergic receptor in complex with heterotrimeric Gi protein
Descriptor: Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Paknejad, N, Alegre, K.O, Su, M, Lou, J.S, Huang, J, Jordan, K.D, Eng, E.T, Meyerson, J.R, Hite, R.K, Huang, X.Y.
Deposit date:2021-08-30
Release date:2021-11-17
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structural basis and mechanism of activation of two different families of G proteins by the same GPCR.
Nat.Struct.Mol.Biol., 28, 2021

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