8S9B

Cryo-EM structure of Nav1.7 with LCM

Summary for 8S9B

• Entry DOI: 10.2210/pdb8s9b/pdb
• EMDB information: 40238
• Descriptor: Sodium channel protein type 9 subunit alpha, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Sodium channel subunit beta-1, ... (11 entities in total)
• Functional Keywords: cryo-em, sodium channel, vgsc, nav1.7, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 288344.72

Authors

Fan, X.,Huang, J.,Yan, N. (deposition date: 2023-03-27, release date: 2023-08-30)

• Primary citation: Wu, Q.,Huang, J.,Fan, X.,Wang, K.,Jin, X.,Huang, G.,Li, J.,Pan, X.,Yan, N.; Structural mapping of Na v 1.7 antagonists.; Nat Commun, 14:3224-3224, 2023; PubMed: 37270609; DOI: 10.1038/s41467-023-38942-3

Experimental method

ELECTRON MICROSCOPY (2.9 Å)