7S0G
Isoproterenol bound beta1 adrenergic receptor in complex with heterotrimeric Gi/s chimera protein
Summary for 7S0G
Entry DOI | 10.2210/pdb7s0g/pdb |
EMDB information | 24790 |
Descriptor | Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short chimera, ... (5 entities in total) |
Functional Keywords | chimera gi/s protein, gpcr-gi-s complex, agonist, signaling protein |
Biological source | Meleagris gallopavo More |
Total number of polymer chains | 4 |
Total formula weight | 146671.07 |
Authors | Paknejad, N.,Alegre, K.O.,Su, M.,Lou, J.S.,Huang, J.,Jordan, K.D.,Eng, E.T.,Meyerson, J.R.,Hite, R.K.,Huang, X.Y. (deposition date: 2021-08-30, release date: 2021-11-17, Last modification date: 2021-12-01) |
Primary citation | Alegre, K.O.,Paknejad, N.,Su, M.,Lou, J.S.,Huang, J.,Jordan, K.D.,Eng, E.T.,Meyerson, J.R.,Hite, R.K.,Huang, X.Y. Structural basis and mechanism of activation of two different families of G proteins by the same GPCR. Nat.Struct.Mol.Biol., 28:936-944, 2021 Cited by PubMed: 34759376DOI: 10.1038/s41594-021-00679-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.86 Å) |
Structure validation
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