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PDB: 853 results

1BLH
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STRUCTURE OF A PHOSPHONATE-INHIBITED BETA-LACTAMASE. AN ANALOG OF THE TETRAHEDRAL TRANSITION STATE(SLASH)INTERMEDIATE OF BETA-LACTAM HYDROLYSIS
Descriptor: BETA-LACTAMASE, [[N-(BENZYLOXYCARBONYL)AMINO]METHYL]PHOSPHATE
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:1993-09-30
Release date:1994-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a phosphonate-inhibited beta-lactamase. An analog of the tetrahedral transition state/intermediate of beta-lactam hydrolysis.
J.Mol.Biol., 234, 1993
1BLC
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BU of 1blc by Molmil
INHIBITION OF BETA-LACTAMASE BY CLAVULANATE: TRAPPED INTERMEDIATES IN CRYOCRYSTALLOGRAPHIC STUDIES
Descriptor: BETA-LACTAMASE, N-(1-CARBOXY-2-HYDROXY-4-OXO-BUTYL)-N-(3-OXO-CISPROPENYL)AMINE, N-(2-HYDROXY-4-OXO-BUTYL)-N-(3-OXO-TRANSPROPENYL)AMINE, ...
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:1993-09-27
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Inhibition of beta-lactamase by clavulanate. Trapped intermediates in cryocrystallographic studies.
J.Mol.Biol., 224, 1992
7MD7
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BU of 7md7 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with triphenylphosphonium analog of chloramphenicol CAM-C4-TPP and protein Y (YfiA) at 2.80A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
Authors:Chen, C.-W, Pavlova, J.A, Lukianov, D.A, Tereshchenkov, A.G, Makarov, G.I, Khairullina, Z.Z, Tashlitsky, V.N, Paleskava, A, Konevega, A.L, Bogdanov, A.A, Osterman, I.A, Sumbatyan, N.V, Polikanov, Y.S.
Deposit date:2021-04-03
Release date:2021-04-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome.
Antibiotics, 10, 2021
1WTO
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BU of 1wto by Molmil
Hyperthermophile chromosomal protein SAC7D double mutant V26F/M29F in complex with DNA GCGATCGC
Descriptor: 5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3', DNA-binding proteins 7a/7b/7d
Authors:Chen, C.-Y, Ko, T.-P, Lin, T.-W, Chou, C.-C, Chen, C.-J, Wang, A.H.-J.
Deposit date:2004-11-29
Release date:2005-02-22
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d
NUCLEIC ACIDS RES., 33, 2005
1WTX
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BU of 1wtx by Molmil
Hyperthermophile chromosomal protein SAC7D single mutant V26A in complex with DNA GTAATTAC
Descriptor: 5'-D(*GP*TP*AP*AP*TP*TP*AP*C)-3', DNA-binding proteins 7a/7b/7d
Authors:Chen, C.-Y, Ko, T.-P, Lin, T.-W, Chou, C.-C, Chen, C.-J, Wang, A.H.-J.
Deposit date:2004-11-29
Release date:2005-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d
NUCLEIC ACIDS RES., 33, 2005
1WTR
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BU of 1wtr by Molmil
Hyperthermophile chromosomal protein SAC7D single mutant M29A in complex with DNA GCGATCGC
Descriptor: 5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3', DNA-binding proteins 7a/7b/7d
Authors:Chen, C.-Y, Ko, T.-P, Lin, T.-W, Chou, C.-C, Chen, C.-J, Wang, A.H.-J.
Deposit date:2004-11-29
Release date:2005-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d
NUCLEIC ACIDS RES., 33, 2005
1WTP
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BU of 1wtp by Molmil
Hyperthermophile chromosomal protein SAC7D single mutant M29F in complex with DNA GCGA(UBr)CGC
Descriptor: 5'-D(*GP*CP*GP*AP*(BRU)P*CP*GP*C)-3', DNA-binding proteins 7a/7b/7d
Authors:Chen, C.-Y, Ko, T.-P, Lin, T.-W, Chou, C.-C, Chen, C.-J, Wang, A.H.-J.
Deposit date:2004-11-29
Release date:2005-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d
NUCLEIC ACIDS RES., 33, 2005
1WTV
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BU of 1wtv by Molmil
Hyperthermophile chromosomal protein SAC7D single mutant M29A in complex with DNA GTAATTAC
Descriptor: 5'-D(*GP*TP*AP*AP*TP*TP*AP*C)-3', DNA-binding proteins 7a/7b/7d
Authors:Chen, C.-Y, Ko, T.-P, Lin, T.-W, Chou, C.-C, Chen, C.-J, Wang, A.H.-J.
Deposit date:2004-11-29
Release date:2005-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d
NUCLEIC ACIDS RES., 33, 2005
1WTW
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BU of 1wtw by Molmil
Hyperthermophile chromosomal protein SAC7D single mutant V26A in complex with DNA GCGATCGC
Descriptor: 5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3', DNA-binding proteins 7a/7b/7d
Authors:Chen, C.-Y, Ko, T.-P, Lin, T.-W, Chou, C.-C, Chen, C.-J, Wang, A.H.-J.
Deposit date:2004-11-29
Release date:2005-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d
NUCLEIC ACIDS RES., 33, 2005
1WTQ
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BU of 1wtq by Molmil
Hyperthermophile chromosomal protein SAC7D single mutant M29F in complex with DNA GTAATTAC
Descriptor: 5'-D(*GP*TP*AP*AP*TP*TP*AP*C)-3', DNA-binding proteins 7a/7b/7d
Authors:Chen, C.-Y, Ko, T.-P, Lin, T.-W, Chou, C.-C, Chen, C.-J, Wang, A.H.-J.
Deposit date:2004-11-29
Release date:2005-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d
NUCLEIC ACIDS RES., 33, 2005
1XYI
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BU of 1xyi by Molmil
Hyperthermophile chromosomal protein Sac7d double mutant Val26Ala/Met29Ala in complex with DNA GCGATCGC
Descriptor: 5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3', DNA-binding proteins 7a/7b/7d
Authors:Chen, C.-Y, Ko, T.-P, Lin, T.-W, Chou, C.-C, Chen, C.-J, Wang, A.H.-J.
Deposit date:2004-11-10
Release date:2005-02-08
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d
Nucleic Acids Res., 33, 2005
1DJC
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BU of 1djc by Molmil
STRUCTURE OF BETA-LACTAMASE PRECURSOR, S70A MUTANT, AT 120K
Descriptor: BETA-LACTAMASE, SULFATE ION
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:1996-08-13
Release date:1997-03-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and kinetics of the beta-lactamase mutants S70A and K73H from Staphylococcus aureus PC1.
Biochemistry, 35, 1996
8SOD
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BU of 8sod by Molmil
Phosphoinositide phosphate 3 kinase gamma bound with ADP and two Gbetagamma subunits in State 1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Chen, C.-L, Tesmer, J.J.G.
Deposit date:2023-04-28
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 2024
8SOE
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BU of 8soe by Molmil
Phosphoinositide phosphate 3 kinase gamma bound with ADP and two Gbetagamma subunits in State 2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Chen, C.-L, Tesmer, J.J.G.
Deposit date:2023-04-28
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 2024
7N6A
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BU of 7n6a by Molmil
Pre-fusion state 1 of EEEV with localized reconstruction
Descriptor: Spike glycoprotein E1, Spike glycoprotein E2
Authors:Chen, C.-L, Kuhn, R.J, Klose, T.
Deposit date:2021-06-07
Release date:2022-06-22
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (14.3 Å)
Cite:Cryo-EM structures of alphavirus conformational intermediates in low pH-triggered prefusion states.
Proc.Natl.Acad.Sci.USA, 119, 2022
7N69
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BU of 7n69 by Molmil
Pre-fusion state 2 of EEEV with localized reconstruction
Descriptor: Spike glycoprotein E1, Spike glycoprotein E2
Authors:Chen, C.-L, Kuhn, R.J, Klose, T.
Deposit date:2021-06-07
Release date:2022-06-22
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (14.1 Å)
Cite:Cryo-EM structures of alphavirus conformational intermediates in low pH-triggered prefusion states.
Proc.Natl.Acad.Sci.USA, 119, 2022
1GHM
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BU of 1ghm by Molmil
Structures of the acyl-enzyme complex of the staphylococcus aureus beta-lactamase mutant GLU166ASP:ASN170GLN with degraded cephaloridine
Descriptor: 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, BETA-LACTAMASE, CARBONATE ION, ...
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:2000-12-19
Release date:2001-04-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structures of the acyl-enzyme complexes of the Staphylococcus aureus beta-lactamase mutant Glu166Asp:Asn170Gln with benzylpenicillin and cephaloridine.
Biochemistry, 40, 2001
8SOC
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BU of 8soc by Molmil
Phosphoinositide phosphate 3 kinase gamma bound with ADP and Gbetagamma
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Chen, C.-L, Tesmer, J.J.G.
Deposit date:2023-04-28
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 2024
8SOA
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BU of 8soa by Molmil
Phosphoinositide phosphate 3 kinase gamma bound with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Phosphoinositide 3-kinase regulatory subunit 5, phosphatidylinositol-4,5-bisphosphate 3-kinase
Authors:Chen, C.-L, Tesmer, J.J.G.
Deposit date:2023-04-28
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 2024
8SOB
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BU of 8sob by Molmil
Phosphoinositide phosphate 3 kinase gamma bound with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Phosphoinositide 3-kinase regulatory subunit 5, phosphatidylinositol-4,5-bisphosphate 3-kinase
Authors:Chen, C.-L, Tesmer, J.J.G.
Deposit date:2023-04-28
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 2024
1KC7
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BU of 1kc7 by Molmil
Pyruvate Phosphate Dikinase with Bound Mg-phosphonopyruvate
Descriptor: MAGNESIUM ION, PHOSPHONOPYRUVATE, SULFATE ION, ...
Authors:Chen, C.C, Howard, A, Herzberg, O.
Deposit date:2001-11-07
Release date:2002-01-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Pyruvate site of pyruvate phosphate dikinase: crystal structure of the enzyme-phosphonopyruvate complex, and mutant analysis
Biochemistry, 41, 2002
8SO9
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BU of 8so9 by Molmil
Phosphoinositide phosphate 3 kinase gamma
Descriptor: Phosphoinositide 3-kinase regulatory subunit 5, phosphatidylinositol-4,5-bisphosphate 3-kinase
Authors:Chen, C.-L, Tesmer, J.J.G.
Deposit date:2023-04-28
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 2024
1KGF
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BU of 1kgf by Molmil
STRUCTURE OF BETA-LACTAMASE ASN 170 GLN MUTANT
Descriptor: BETA-LACTAMASE
Authors:Chen, C.C.H, Zawadzke, L.E, Herzberg, O.
Deposit date:1996-10-17
Release date:1997-03-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Elimination of the hydrolytic water molecule in a class A beta-lactamase mutant: crystal structure and kinetics.
Biochemistry, 35, 1996
1KGE
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BU of 1kge by Molmil
STRUCTURE OF BETA-LACTAMASE ASN 170 MET MUTANT
Descriptor: BETA-LACTAMASE
Authors:Chen, C.C.H, Zawadzke, L.E, Herzberg, O.
Deposit date:1996-10-17
Release date:1997-04-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Elimination of the hydrolytic water molecule in a class A beta-lactamase mutant: crystal structure and kinetics.
Biochemistry, 35, 1996
1GHI
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BU of 1ghi by Molmil
STRUCTURE OF BETA-LACTAMASE GLU166ASP:ASN170GLN MUTANT
Descriptor: BETA-LACTAMASE, CARBONATE ION
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:2000-12-18
Release date:2001-04-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of the acyl-enzyme complexes of the Staphylococcus aureus beta-lactamase mutant Glu166Asp:Asn170Gln with benzylpenicillin and cephaloridine.
Biochemistry, 40, 2001

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