8SOC
Phosphoinositide phosphate 3 kinase gamma bound with ADP and Gbetagamma
Summary for 8SOC
| Entry DOI | 10.2210/pdb8soc/pdb |
| EMDB information | 40653 |
| Descriptor | phosphatidylinositol-4,5-bisphosphate 3-kinase, Phosphoinositide 3-kinase regulatory subunit 5, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (5 entities in total) |
| Functional Keywords | phosphoinositide 3-kinase, chemotaxis, cancer, signaling protein |
| Biological source | Sus scrofa (pig) More |
| Total number of polymer chains | 4 |
| Total formula weight | 272589.39 |
| Authors | Chen, C.-L.,Tesmer, J.J.G. (deposition date: 2023-04-28, release date: 2024-04-03, Last modification date: 2024-04-17) |
| Primary citation | Chen, C.L.,Syahirah, R.,Ravala, S.K.,Yen, Y.C.,Klose, T.,Deng, Q.,Tesmer, J.J.G. Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38565696DOI: 10.1038/s41594-024-01265-y PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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