8SOC
Phosphoinositide phosphate 3 kinase gamma bound with ADP and Gbetagamma
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | phosphatidylinositol-4,5-bisphosphate 3-kinase | polymer | 1108 | 127573.5 | 1 | UniProt (A0A8D1WUA4) Pfam (PF19710) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB | Sus scrofa (pig) | |
| 2 | B | Phosphoinositide 3-kinase regulatory subunit 5 | polymer | 890 | 98497.8 | 1 | UniProt (A0A8D0T2D6) Pfam (PF10486) In PDB | Sus scrofa (pig) | |
| 3 | C | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62871) Pfam (PF00400) In PDB | Bos taurus (cattle) | Transducin beta chain 1 |
| 4 | G | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 77 | 8674.0 | 1 | UniProt (P63212) Pfam (PF00631) In PDB | Bos taurus (cattle) | G gamma-I |
| 5 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence modifications
A: 2 - 1102 (UniProt: A0A8D1WUA4)
B: 1 - 877 (UniProt: A0A8D0T2D6)
G: 1 - 71 (UniProt: P63212)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | initiating methionine |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 878 | - | expression tag |
| Gly 879 | - | expression tag |
| Gly 880 | - | expression tag |
| Gly 881 | - | expression tag |
| Ser 882 | - | expression tag |
| Asp 883 | - | expression tag |
| Tyr 884 | - | expression tag |
| Lys 885 | - | expression tag |
| Asp 886 | - | expression tag |
| Asp 887 | - | expression tag |
| Asp 888 | - | expression tag |
| Asp 889 | - | expression tag |
| Lys 890 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 68 | Cys 68 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 272162.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 427.2 | |
| All* | Total formula weight | 272589.4 |
