4GOY
The crystal structure of human fascin 1 K41A mutant
Summary for 4GOY
Entry DOI | 10.2210/pdb4goy/pdb |
Related | 4GOV 4GP0 4GP3 |
Descriptor | Fascin, BROMIDE ION, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | beta-trefoil, actin bundling protein, cancer, metastasis, cell migration, actin-binding, phosphoprotein, protein binding, actin |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton: Q16658 |
Total number of polymer chains | 2 |
Total formula weight | 110788.12 |
Authors | Yang, S.Y.,Huang, F.K.,Huang, J.,Chen, S.,Jakoncic, J.,Leo-Macias, A.,Diaz-Avalos, R.,Chen, L.,Zhang, J.J.,Huang, X.Y. (deposition date: 2012-08-20, release date: 2012-11-28, Last modification date: 2023-09-13) |
Primary citation | Yang, S.,Huang, F.K.,Huang, J.,Chen, S.,Jakoncic, J.,Leo-Macias, A.,Diaz-Avalos, R.,Chen, L.,Zhang, J.J.,Huang, X.Y. Molecular mechanism of fascin function in filopodial formation. J.Biol.Chem., 288:274-284, 2013 Cited by PubMed: 23184945DOI: 10.1074/jbc.M112.427971 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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