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PDB: 65 results

4V9C
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BU of 4v9c by Molmil
Allosteric control of the ribosome by small-molecule antibiotics
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Cate, J.H.D, Pulk, A, Blanchard, S.C, Wang, L, Feldman, M.B, Wasserman, M.R, Altman, R.
Deposit date:2012-07-25
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Allosteric control of the ribosome by small-molecule antibiotics.
Nat.Struct.Mol.Biol., 19, 2012
8EIU
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BU of 8eiu by Molmil
E. coli 70S ribosome with A-loop mutations U2554C and U2555C
Descriptor: 16S rRNA, 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ...
Authors:Nissley, A.J, Penev, P.I, Watson, Z.L, Banfield, J.F, Cate, J.H.D.
Deposit date:2022-09-15
Release date:2023-02-01
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.24 Å)
Cite:Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome.
Nucleic Acids Res., 51, 2023
6U48
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BU of 6u48 by Molmil
E. coli 50S with phazolicin (PHZ) bound in exit tunnel
Descriptor: 23S rRNA, 50S ribosomal protein bL17, 50S ribosomal protein bL19, ...
Authors:Watson, Z.L, Cate, J.H.D, Polikanov, Y.S, Severinov, K.
Deposit date:2019-08-23
Release date:2019-09-18
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Structure of ribosome-bound azole-modified peptide phazolicin rationalizes its species-specific mode of bacterial translation inhibition.
Nat Commun, 10, 2019
6I7V
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Ribosomal protein paralogs bL31 and bL36
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
Authors:Pulk, A, Cate, J.H.D, Remme, J, Lilleorg, S, Reier, K, Peil, L, Liiv, A, Tammsalu, T.
Deposit date:2018-11-19
Release date:2018-12-05
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Bacterial ribosome heterogeneity: Changes in ribosomal protein composition during transition into stationary growth phase.
Biochimie, 156, 2018
7K00
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BU of 7k00 by Molmil
Structure of the Bacterial Ribosome at 2 Angstrom Resolution
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Watson, Z.L, Ward, F.R, Meheust, R, Ad, O, Schepartz, A, Banfield, J.F, Cate, J.H.D.
Deposit date:2020-09-02
Release date:2020-09-23
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.98 Å)
Cite:Structure of the bacterial ribosome at 2 angstrom resolution.
Elife, 9, 2020
8EMM
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BU of 8emm by Molmil
Composite 70S ribosome structure for "Atomistic simulations of the E. coli ribosome provide selection criteria for translationally active substrates
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Watson, Z.L, Cate, J.H.D.
Deposit date:2022-09-28
Release date:2023-05-31
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Atomistic simulations of the Escherichia coli ribosome provide selection criteria for translationally active substrates.
Nat.Chem., 15, 2023
8G6X
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BU of 8g6x by Molmil
Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site meta-aminobenzoic acid charged NH-tRNAPhe
Descriptor: 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), 3-aminobenzamide, ...
Authors:Majumdar, C, Cate, J.H.D.
Deposit date:2023-02-16
Release date:2023-03-22
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.31 Å)
Cite:Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8G6W
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BU of 8g6w by Molmil
Structure of WT E.coli 70S ribosome complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site ortho-aminobenzoic acid charged NH-tRNAPhe
Descriptor: 16S rRNA, 2-AMINO-BENZAMIDE, 23S rRNA, ...
Authors:Majumdar, C, Cate, J.H.D.
Deposit date:2023-02-16
Release date:2023-04-05
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.02 Å)
Cite:Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8G6Y
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BU of 8g6y by Molmil
Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site 3-aminopyridine-4-carboxylic acid charged NH-tRNAPhe
Descriptor: 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), 3-aminopyridine-4-carboxamide, ...
Authors:Majumdar, C, Cate, J.H.D.
Deposit date:2023-02-16
Release date:2023-04-05
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.09 Å)
Cite:Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8FTO
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BU of 8fto by Molmil
E. coli 70S ribosome with an improved MS2 tag inserted in H98
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Nissley, A.J, Cate, J.H.D.
Deposit date:2023-01-12
Release date:2023-08-02
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.85 Å)
Cite:Interactions between terminal ribosomal RNA helices stabilize the E. coli large ribosomal subunit.
Rna, 29, 2023
5K4B
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BU of 5k4b by Molmil
Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 1
Descriptor: CHLORIDE ION, Eukaryotic translation initiation factor 3 subunit D
Authors:Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D.
Deposit date:2016-05-20
Release date:2016-07-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
5K4D
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BU of 5k4d by Molmil
Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 3
Descriptor: Eukaryotic translation initiation factor 3 subunit D
Authors:Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D.
Deposit date:2016-05-20
Release date:2016-07-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
6OLI
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BU of 6oli by Molmil
Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLF
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BU of 6olf by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OM0
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BU of 6om0 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-17
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLE
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BU of 6ole by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OM7
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BU of 6om7 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-18
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLZ
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BU of 6olz by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-17
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLG
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BU of 6olg by Molmil
Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
5K4C
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BU of 5k4c by Molmil
Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 2
Descriptor: Eukaryotic translation initiation factor 3 subunit D, GLYCEROL
Authors:Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D.
Deposit date:2016-05-20
Release date:2016-07-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
1VBY
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BU of 1vby by Molmil
Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, and Mn2+ bound
Descriptor: Hepatitis Delta virus ribozyme, MANGANESE (II) ION, SODIUM ION, ...
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC0
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BU of 1vc0 by Molmil
Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Imidazole and Sr2+ solution
Descriptor: Hepatitis Delta virus ribozyme, STRONTIUM ION, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC6
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BU of 1vc6 by Molmil
Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Product with C75U Mutaion, cleaved in Imidazole and Mg2+ solutions
Descriptor: Hepatitis Delta virus ribozyme, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-04
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VBX
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BU of 1vbx by Molmil
Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in EDTA solution
Descriptor: Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC5
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BU of 1vc5 by Molmil
Crystal Structure of the Wild Type Hepatitis Delta Virus Gemonic Ribozyme Precursor, in EDTA solution
Descriptor: Hepatitis Delta virus ribozyme, SODIUM ION, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-04
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004

 

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