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8G6Y

Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site 3-aminopyridine-4-carboxylic acid charged NH-tRNAPhe

Summary for 8G6Y
Entry DOI10.2210/pdb8g6y/pdb
Related8G6W 8G6X
EMDB information29788 29807
Descriptor50S ribosomal protein L33, 5S rRNA, 50S ribosomal protein L2, ... (41 entities in total)
Functional Keywordsribosome, non-natural monomers, aminobenzoic acids, unnatural monomers
Biological sourceEscherichia coli
More
Total number of polymer chains34
Total formula weight1415807.92
Authors
Majumdar, C.,Cate, J.H.D. (deposition date: 2023-02-16, release date: 2023-04-05, Last modification date: 2023-11-15)
Primary citationMajumdar, C.,Walker, J.A.,Francis, M.B.,Schepartz, A.,Cate, J.H.D.
Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9:1160-1169, 2023
Cited by
PubMed: 37396857
DOI: 10.1021/acscentsci.3c00153
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.09 Å)
Structure validation

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