8G6Y
Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site 3-aminopyridine-4-carboxylic acid charged NH-tRNAPhe
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (0) | 50S ribosomal protein L33 | polymer | 55 | 6388.6 | 1 | UniProt (F4NQ61) Pfam (PF00471) UniProt (by SIFTS) (P0A7N9) | Escherichia coli | |
| 2 | B (1) | 50S ribosomal protein L34 | polymer | 46 | 5397.5 | 1 | UniProt (B7MGC4) Pfam (PF00468) UniProt (by SIFTS) (P0A7P5) | Escherichia coli | |
| 3 | C (2) | 50S ribosomal protein L35 | polymer | 65 | 7313.0 | 1 | UniProt (P0A7Q1) Pfam (PF01632) | Escherichia coli | Large ribosomal subunit protein bL35,Ribosomal protein A |
| 4 | D (3) | 50S ribosomal protein L36 | polymer | 38 | 4377.4 | 1 | UniProt (A0A0E2L017) Pfam (PF00444) UniProt (by SIFTS) (P0A7Q6) | Escherichia coli | |
| 5 | E (4) | 50S ribosomal protein L31 | polymer | 70 | 7887.1 | 1 | UniProt (P0A7M9) Pfam (PF01197) | Escherichia coli | Large ribosomal subunit protein bL31-A |
| 6 | F (X) | mRNA | polymer | 28 | 9036.4 | 1 | Escherichia coli | ||
| 7 | G (Y) | A-site tRNA Phe | polymer | 76 | 24485.5 | 1 | GenBank (1315725308) | Escherichia coli | |
| 8 | H (Z) | P-site tRNA fMet | polymer | 76 | 24513.6 | 1 | GenBank (1804121330) | Escherichia coli | |
| 9 | I (a) | 23S rRNA | polymer | 2904 | 941811.6 | 1 | Escherichia coli | ||
| 10 | J (b) | 5S rRNA | polymer | 120 | 38790.1 | 1 | GenBank (1273279017) | Escherichia coli | |
| 11 | K (c) | 50S ribosomal protein L2 | polymer | 273 | 29923.6 | 1 | UniProt (P60422) Pfam (PF00181) Pfam (PF03947) | Escherichia coli | Large ribosomal subunit protein uL2 |
| 12 | L (d) | 50S ribosomal protein L3 | polymer | 209 | 22291.6 | 1 | UniProt (U9Y9G2) Pfam (PF00297) UniProt (by SIFTS) (P60438) | Escherichia coli | |
| 13 | M (e) | 50S ribosomal protein L4 | polymer | 201 | 22121.6 | 1 | UniProt (A1AGK6) Pfam (PF00573) UniProt (by SIFTS) (P60723) | Escherichia coli | |
| 14 | N (f) | 50S ribosomal protein L5 | polymer | 179 | 20333.6 | 1 | UniProt (A0A829CFT8) Pfam (PF00281) Pfam (PF00673) UniProt (by SIFTS) (P62399) | Escherichia coli | |
| 15 | O (g) | 50S ribosomal protein L6 | polymer | 177 | 18932.8 | 1 | UniProt (A0A862ZNS7) Pfam (PF00347) UniProt (by SIFTS) (P0AG55) | Escherichia coli | |
| 16 | P (h) | 50S ribosomal protein L9 | polymer | 149 | 15789.0 | 1 | UniProt (V0YZK9) Pfam (PF01281) Pfam (PF03948) UniProt (by SIFTS) (P0A7R1) | Escherichia coli | |
| 17 | Q (i) | 50S ribosomal protein L13 | polymer | 142 | 16050.6 | 1 | UniProt (S1EW51) Pfam (PF00572) UniProt (by SIFTS) (P0AA10) | Escherichia coli | |
| 18 | R (j) | 50S ribosomal protein L14 | polymer | 123 | 13565.1 | 1 | UniProt (S1NW45) Pfam (PF00238) UniProt (by SIFTS) (P0ADY3) | Escherichia coli | |
| 19 | S (k) | 50S ribosomal protein L15 | polymer | 144 | 15008.5 | 1 | UniProt (A0A037Y8L6) Pfam (PF00828) UniProt (by SIFTS) (P02413) | Escherichia coli | |
| 20 | T (l) | 50S ribosomal protein L16 | polymer | 136 | 15329.3 | 1 | UniProt (A1AGK1) Pfam (PF00252) UniProt (by SIFTS) (P0ADY7) | Escherichia coli | |
| 21 | U (m) | 50S ribosomal protein L17 | polymer | 127 | 14393.7 | 1 | UniProt (A0A1X3LC97) Pfam (PF01196) UniProt (by SIFTS) (P0AG44) | Escherichia coli | |
| 22 | V (n) | 50S ribosomal protein L18 | polymer | 117 | 12794.7 | 1 | UniProt (E3PKY8) Pfam (PF00861) UniProt (by SIFTS) (P0C018) | Escherichia coli | |
| 23 | W (o) | 50S ribosomal protein L19 | polymer | 115 | 13159.3 | 1 | UniProt (V0AJX1) Pfam (PF01245) UniProt (by SIFTS) (P0A7K6) | Escherichia coli | |
| 24 | X (p) | 50S ribosomal protein L20 | polymer | 118 | 13528.0 | 1 | UniProt (B7MAS6) Pfam (PF00453) UniProt (by SIFTS) (P0A7L3) | Escherichia coli | |
| 25 | Y (q) | Ribosomal protein L21 | polymer | 103 | 11586.4 | 1 | UniProt (A0A829CSJ4) Pfam (PF00829) UniProt (by SIFTS) (P0AG48) | Escherichia coli | |
| 26 | Z (r) | 50S ribosomal protein L22 | polymer | 110 | 12253.4 | 1 | UniProt (P61175) Pfam (PF00237) | Escherichia coli | Large ribosomal subunit protein uL22 |
| 27 | AA (s) | 50S ribosomal protein L23 | polymer | 100 | 11222.2 | 1 | UniProt (A0A829CFV1) Pfam (PF00276) UniProt (by SIFTS) (P0ADZ0) | Escherichia coli | |
| 28 | BA (t) | 50S ribosomal protein L24 | polymer | 104 | 11339.3 | 1 | UniProt (A0A1X3KWX7) Pfam (PF00467) Pfam (PF17136) UniProt (by SIFTS) (P60624) | Escherichia coli | |
| 29 | CA (u) | 50S ribosomal protein L25 | polymer | 94 | 10713.5 | 1 | UniProt (D7XH79) Pfam (PF01386) UniProt (by SIFTS) (P68919) | Escherichia coli | |
| 30 | DA (v) | 50S ribosomal protein L27 | polymer | 85 | 9146.5 | 1 | UniProt (P0A7L8) Pfam (PF01016) | Escherichia coli | Large ribosomal subunit protein bL27 |
| 31 | EA (w) | 50S ribosomal protein L28 | polymer | 78 | 9027.6 | 1 | UniProt (A0A1X3JA73) Pfam (PF00830) UniProt (by SIFTS) (P0A7M2) | Escherichia coli | |
| 32 | FA (x) | 50S ribosomal protein L29 | polymer | 63 | 7286.5 | 1 | UniProt (D6IEL0) Pfam (PF00831) UniProt (by SIFTS) (P0A7M6) | Escherichia coli | |
| 33 | GA (y) | 50S ribosomal protein L30 | polymer | 59 | 6554.8 | 1 | UniProt (V0YKA9) Pfam (PF00327) UniProt (by SIFTS) (P0AG51) | Escherichia coli | |
| 34 | HA (z) | 50S ribosomal protein L32 | polymer | 57 | 6463.4 | 1 | UniProt (D7XI28) Pfam (PF01783) UniProt (by SIFTS) (P0A7N4) | Escherichia coli | |
| 35 | IA, JA (3, 4) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 36 | KA (Y) | 3-aminopyridine-4-carboxamide | non-polymer | 137.1 | 1 | Chemie (YRW) | |||
| 37 | LA (Z) | 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate) | non-polymer | 346.2 | 1 | Chemie (8AN) | |||
| 38 | MA (Z) | N-FORMYLMETHIONINE | non-polymer | 177.2 | 1 | Chemie (FME) | |||
| 39 | AB, AC, AD, AE, AF... (a, b, d, z) | MAGNESIUM ION | non-polymer | 24.3 | 231 | Chemie (MG) | |||
| 40 | HI, II, JI, KI, LI... (a, c) | POTASSIUM ION | non-polymer | 39.1 | 15 | Chemie (K) | |||
| 41 | AK, BK, CK, DK, EK... (1, 2, 3, Z, a...) | water | water | 18.0 | 3460 | Chemie (HOH) |
Sequence modifications
l: 1 - 136 (UniProt: A1AGK1)
| PDB | External Database | Details |
|---|---|---|
| Ms6 82 | Met 82 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 34 |
| Total formula weight | 1408815.6 | |
| Non-Polymers* | Number of molecules | 251 |
| Total formula weight | 6992.3 | |
| All* | Total formula weight | 1415807.9 |
